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Journal of Zhejiang University SCIENCE A 2000 Vol.1 No.4 P.448-455

http://doi.org/10.1631/jzus.2000.0448


IN VIVO INHIBITION AND RECOVERY OF BRAIN ACETYLCHOLINES-TERASE IN TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) FOLLOWING EXPOSURE TO FENITROTHION


Author(s):  Sorsa Sota Solomon, LI Shao-nan, FANG De-fan

Affiliation(s):  Institute of Pesticide Environmental Toxicology, Dept. of Plant Protection, Zhejiang University, Hangzhou 310029

Corresponding email(s): 

Key Words:  acetylcholinesterase, fenitrothion, fish, inhibition, recovery


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Sorsa Sota Solomon, LI Shao-nan, FANG De-fan. IN VIVO INHIBITION AND RECOVERY OF BRAIN ACETYLCHOLINES-TERASE IN TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) FOLLOWING EXPOSURE TO FENITROTHION[J]. Journal of Zhejiang University Science A, 2000, 1(4): 448-455.

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author="Sorsa Sota Solomon, LI Shao-nan, FANG De-fan",
journal="Journal of Zhejiang University Science A",
volume="1",
number="4",
pages="448-455",
year="2000",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2000.0448"
}

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%A Sorsa Sota Solomon
%A LI Shao-nan
%A FANG De-fan
%J Journal of Zhejiang University SCIENCE A
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%P 448-455
%@ 1869-1951
%D 2000
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2000.0448

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T1 - IN VIVO INHIBITION AND RECOVERY OF BRAIN ACETYLCHOLINES-TERASE IN TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) FOLLOWING EXPOSURE TO FENITROTHION
A1 - Sorsa Sota Solomon
A1 - LI Shao-nan
A1 - FANG De-fan
J0 - Journal of Zhejiang University Science A
VL - 1
IS - 4
SP - 448
EP - 455
%@ 1869-1951
Y1 - 2000
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2000.0448


Abstract: 
Freshwater fish, topmouth gudgeon (Pseudorasobora parva), were pretreated with piperronyl butoxide (PBO) or triphenyl phosphate (TPP) and then exposed to different concentrations of fenitrothion (FNT) in a static system. Evaluation of brain acetylcholinesterase (AchE) activity after 24, 48 and 96 h pesticide exposure indicated that AchE activity decreased as the concentration increased. fish pretreated with TPP exhibited significantly decreased AchE activity whilst in the PBO pretreated group, increased activity was observed as compared with those exposed to FNT alone. The pattern of AchE recovery was also assessed in fish previously exposed for 96h and then transferred to clean (chemical free) water. Following 8 days of recovery period, the AchE activity of those exposed to FNT alone and pretreated with TPP was still lower than that of the control. This study showed that FNT may cause hazard to fish after field application.

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