CLC number: R540.41
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 0000-00-00
Cited: 9
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TAO Ze-wei, HUANG Yuan-wei, XIA Qiang, FU Jun, ZHAO Zhi-hong, LU Xian, BRUCE I.C.. Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction[J]. Journal of Zhejiang University Science A, 2004, 5(4): 494-498.
@article{title="Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction",
author="TAO Ze-wei, HUANG Yuan-wei, XIA Qiang, FU Jun, ZHAO Zhi-hong, LU Xian, BRUCE I.C.",
journal="Journal of Zhejiang University Science A",
volume="5",
number="4",
pages="494-498",
year="2004",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2004.0494"
}
%0 Journal Article
%T Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction
%A TAO Ze-wei
%A HUANG Yuan-wei
%A XIA Qiang
%A FU Jun
%A ZHAO Zhi-hong
%A LU Xian
%A BRUCE I.C.
%J Journal of Zhejiang University SCIENCE A
%V 5
%N 4
%P 494-498
%@ 1869-1951
%D 2004
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2004.0494
TY - JOUR
T1 - Early association of electrocardiogram alteration with infarct size and cardiac function after myocardial infarction
A1 - TAO Ze-wei
A1 - HUANG Yuan-wei
A1 - XIA Qiang
A1 - FU Jun
A1 - ZHAO Zhi-hong
A1 - LU Xian
A1 - BRUCE I.C.
J0 - Journal of Zhejiang University Science A
VL - 5
IS - 4
SP - 494
EP - 498
%@ 1869-1951
Y1 - 2004
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2004.0494
Abstract: Objective: myocardial infarction (MI) is the main cause of heart failure, but the relationship between the extent of MI and cardiac function has not been clearly determined. The present study was undertaken to investigate early changes in the electrocardiogram associated with infarct size and cardiac function after MI.Methods: MI was induced by ligating the left anterior descending coronary artery in rats. electrocardiograms, echocardiographs and hemodynamic parameters were assessed and myocardial infarct size was measured from mid-transverse sections stained with Masson's trichrome. Results: The sum of pathological Q wave amplitudes was strongly correlated with myocardial infarct size (r = 0.920, P < 0.0001), left ventricular ejection fraction (r = -0.868, P < 0.0001) and left ventricular end diastolic pressure (r = 0.835, P < 0.0004). Furthermore, there was close relationship between MI size and cardiac function as assessed by left ventricular ejection fraction (r = -0.913, P < 0.0001) and left ventricular end diastolic pressure (r = 0.893, P < 0.0001). Conclusion: The sum of pathological Q wave amplitudes after MI can be used to estimate the extent of MI as well as cardiac function.
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