Full Text:   <2370>

CLC number: R73

On-line Access: 

Received: 2007-11-18

Revision Accepted: 2007-12-03

Crosschecked: 0000-00-00

Cited: 7

Clicked: 4414

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
1. Reference List
Open peer comments

Journal of Zhejiang University SCIENCE B 2008 Vol.9 No.1 P.39~43

http://doi.org/10.1631/jzus.B072258


Breast metastasis from small cell lung carcinoma


Author(s):  Shi-ping LUH, Chih KUO, Thomas Chang-yao TSAO

Affiliation(s):  Department of Surgery, Chia-Yi Christian Hospital and Chung-Shan Medical University and Hospital, Taichung 402, Taiwan, China; more

Corresponding email(s):   luh572001@yahoo.com.tw

Key Words:  Small cell carcinoma, Breast metastasis, Lung


Shi-ping LUH, Chih KUO, Thomas Chang-yao TSAO. Breast metastasis from small cell lung carcinoma[J]. Journal of Zhejiang University Science B, 2008, 9(1): 39~43.

@article{title="Breast metastasis from small cell lung carcinoma",
author="Shi-ping LUH, Chih KUO, Thomas Chang-yao TSAO",
journal="Journal of Zhejiang University Science B",
volume="9",
number="1",
pages="39~43",
year="2008",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B072258"
}

%0 Journal Article
%T Breast metastasis from small cell lung carcinoma
%A Shi-ping LUH
%A Chih KUO
%A Thomas Chang-yao TSAO
%J Journal of Zhejiang University SCIENCE B
%V 9
%N 1
%P 39~43
%@ 1673-1581
%D 2008
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B072258

TY - JOUR
T1 - Breast metastasis from small cell lung carcinoma
A1 - Shi-ping LUH
A1 - Chih KUO
A1 - Thomas Chang-yao TSAO
J0 - Journal of Zhejiang University Science B
VL - 9
IS - 1
SP - 39
EP - 43
%@ 1673-1581
Y1 - 2008
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B072258


Abstract: 
Breast metastases from extramammary neoplasms are very rare. We presented a 66 year-old female with metastasis of small cell lung carcinoma to the breast. She presented with consolidation over the left upper lobe of her lung undetermined after endobronchial or video-assisted thoracoscopic surgery (VATS) biopsy, and this was treated effectively after antibiotic therapy at initial stage. The left breast lumps were noted 4 months later, and she underwent a modified radical mastectomy under the impression of primary breast carcinoma. However, the subsequent chest imaging revealed re-growing mass over the left mediastinum and hilum, and cells with the same morphological and staining features were found from specimens of transbronchial brushing and biopsy. An accurate diagnosis to distinguish a primary breast carcinoma from metastatic one is very important because the therapeutic planning and the outcome between them are different.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1] Adegbola, T., Connolly, C.E., Mortimer, G., 2005. Small cell neuroendocrine carcinoma of the breast: a report of three cases and review of the literature. J. Clin. Pathol., 58(7):775-778.

[2] Ajisaka, H., Maeda, K., Miwa, A., Yamamoto, K., 2003. Breast cancer with endocrine differentiation: report of two cases showing different histologic patterns. Surg. Today, 33(12):909-912.

[3] Cangiarella, J., Symmans, W.F., Cohen, J.M., Goldenberg, A., Shapiro, R.L., Waisman, J., 1998. Malignant melanoma metastatic to the breast: a report of seven cases diagnosed by fine-needle aspiration cytology. Cancer, 84(3):160-162.

[4] Chaignaud, B., Hall, T.J., Powers, C., Subramony, C., Scott-Conner, C.E., 1994. Diagnosis and natural history of extramammary tumors metastatic to the breast. J. Am. Coll. Surg., 179(1):49-53.

[5] Galanis, E., Frytak, S., Lloyd, R.V., 1997. Extrapulmonary small cell carcinoma. Cancer, 79(9):1729-1736.

[6] Haider, K., Shahid, R.K., Finch, D., Sami, A., Ahmad, I., Yadav, S., Alvi, R., Popkin, D., Ahmed, S., 2006. Extrapulmonary small cell cancer: a Canadian province’s experience. Cancer, 107(9):2262-2269.

[7] Hajdu, S.I., Urban, J.A., 1972. Cancers metastatic to the breast. Cancer, 29(6):1691-1696.

[8] Inoue, T., Tanaka, E., Sakuramoto, M., Minakuchi, M., Maeda, Y., Maniwa, K., Terada, K., Goto, S., Takeda, T., Okamoto, M., et al., 2006. A case of small cell lung cancer with an initial symptom of breast metastasis. Nihon Kokyuki Gakkai Zasshi, 44(1):39-42.

[9] Jakovljević, B., Stevanović, O., Bacić, G., 2003. Metastases to the breast from small-cell lung cancer: MR findings. A case report. Acta Radiol., 44(5):485-488.

[10] Kelly, C., Henderson, D., Corris, P., 1988. Breast lumps. Rare presentation of oat cell carcinoma of lung. J. Clin. Pathol., 41(2):171-172.

[11] Kim, J.H., Lee, S.H., Park, J., Kim, H.Y., Lee, S.I., Nam, E.M., Park, J.O., Kim, K., Jung, C.W., Im, Y.H., et al., 2004. Extrapulmonary small-cell carcinoma: a single-institution experience. Jpn. J. Clin. Oncol., 34(5):250-254.

[12] Masmoudi, A., Mathieu, M.C., Soria, J.C., 2003. Breast metastasis from lung adenocarcinoma: a case report. Anticancer Res., 23(2C):1825-1826.

[13] Mihai, R., Christie-Brown, J., Bristol, J., 2005. Breast metastases from colorectal carcinoma. Breast, 14(1):80-81.

[14] Nielsen, M., Andersen, J.A., Henriksen, F.W., Kristensen, P.B., Lorentzen, M., Ravn, V., Schiødt, T., Thorborg, J.V., Ornvold, K., 1981. Metastases to the breast from extramammary carcinomas. Acta Pathol. Microbiol. Scand. A, 89(4):251-256.

[15] Oksüzoğlu, B., Abali, H., Güler, N., Baltali, E., Ozişik, Y., 2003. Metastasis to the breast from nonmammarian solid neoplasms: a report of five cases. Med. Oncol., 20(3):295-300.

[16] Ramar, K., Pervez, H., Potti, A., Mehdi, S., 2003. Breast metastasis from non-small-cell lung carcinoma. Med. Oncol., 20(2):181-184.

[17] Ribeiro-Silva, A., Mendes, C.F., Costa, I.S., de Moura, H.B., Tiezzi, D.G., Andrade, J.M., 2006. Metastases to the breast from extramammary malignancies: a clinicopathologic study of 12 cases. Pol. J. Pathol., 57(3):161-165.

[18] Sadikot, R.T., Renwick, D.S., DaCosta, P., Chalmers, A.G., Pearson, S.B., 1997. Breast metastasis from non-small cell lung cancer. South. Med. J., 90(10):1063-1064.

[19] Santeufemia, D.A., Piredda, G., Fadda, G.M., Cossu Rocca, P., Costantino, S., Sanna, G., Sarobba, M.G., Pinna, M.A., Putzu, C., Farris, A., 2006. Successful outcome after combined chemotherapeutic and surgical management in a case of esophageal cancer with breast and brain relapse. World J. Gastroenterol., 12(34):5565-5568.

[20] Shin, S.J., DeLellis, R.A., Ying, L., Rosen, P.P., 2000. Small cell carcinoma of the breast: a clinicopathologic and immunohistochemical study of nine patients. Am. J. Surg. Pathol., 24(9):1231-1238.

[21] Shukla, R., Pooja, B., Radhika, S., Nijhawan, R., Rajwanshi, A., 2005. Fine-needle aspiration cytology of extramammary neoplasms metastatic to the breast. Diagn. Cytopathol., 32(4):193-197.

[22] Silverman, J.F., Feldman, P.S., Covell, J.L., Frable, W.J., 1987. Fine needle aspiration cytology of neoplasms metastatic to the breast. Acta Cytol., 31(3):291-300.

[23] Sridhar, P., Matey, P., Aluwihare, N., 2004. Primary carcinoma of breast with small-cell differentiation. Breast, 13(2):149-151.

[24] Vizcaíno, I., Torregrosa, A., Higueras, V., Morote, V., Cremades, A., Torres, V., Olmos, S., Molins, C., 2001. Metastasis to the breast form extramammary malignancies. A report of four cases and a review of literature. Eur. Radiol., 11(9):1659-1665.

[25] Yeh, C.N., Lin, C.H., Chen, M.F., 2004. Clinical and ultrasonographic characteristics of breast metastases from extramammary malignancies. Am. Surg., 70(4):287-290.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - Journal of Zhejiang University-SCIENCE