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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.1 P.67~76

http://doi.org/10.1631/jzus.B0820256


Mycoplasma lipoproteins and Toll-like receptors


Author(s):  Ling-ling ZUO, Yi-mou WU, Xiao-xing YOU

Affiliation(s):  Institute of Pathogenic Biology, School of Medicine, University of South China, Hengyang 421001, China

Corresponding email(s):   yimouwu@sina.com

Key Words:  Mycoplasma lipoproteins/lipopeptides, Toll-like receptors, Signal pathway, Mycoplasmal pathogenic mechanism


Ling-ling ZUO, Yi-mou WU, Xiao-xing YOU. Mycoplasma lipoproteins and Toll-like receptors[J]. Journal of Zhejiang University Science B, 2009, 10(1): 67~76.

@article{title="Mycoplasma lipoproteins and Toll-like receptors",
author="Ling-ling ZUO, Yi-mou WU, Xiao-xing YOU",
journal="Journal of Zhejiang University Science B",
volume="10",
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pages="67~76",
year="2009",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0820256"
}

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%T Mycoplasma lipoproteins and Toll-like receptors
%A Ling-ling ZUO
%A Yi-mou WU
%A Xiao-xing YOU
%J Journal of Zhejiang University SCIENCE B
%V 10
%N 1
%P 67~76
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%D 2009
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820256

TY - JOUR
T1 - Mycoplasma lipoproteins and Toll-like receptors
A1 - Ling-ling ZUO
A1 - Yi-mou WU
A1 - Xiao-xing YOU
J0 - Journal of Zhejiang University Science B
VL - 10
IS - 1
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EP - 76
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Y1 - 2009
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0820256


Abstract: 
Mycoplasmas, the smallest free-living, self-replicating bacteria with diameters of 200 to 800 nm, have been reported to be associated with human diseases. It is well known that the mycoplasma lipoprotein/peptide is able to modulate the host immune system, whose N-terminal structure is an important factor in inducing immunity and distinguishing toll-like receptors (TLRs). However, there is still no clear elucidation about the pathogenic mechanism of mycoplasma lipoprotein/peptide and the signaling pathway. Some researchers have focused on understanding the structures of these proteins and the relationships between their structure and biological function. This review provides an update on the research in this field.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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