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CLC number: R453.9

On-line Access: 2012-08-01

Received: 2012-06-18

Revision Accepted: 2012-07-09

Crosschecked: 2012-07-18

Cited: 4

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Journal of Zhejiang University SCIENCE B 2012 Vol.13 No.8 P.638-644

10.1631/jzus.B1201005


Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention


Author(s):  Jian-ping Li, Mohetaboer Momin, Yong Huo, Chun-yan Wang, Yan Zhang, Yan-jun Gong, Zhao-ping Liu, Xin-gang Wang, Bo Zheng

Affiliation(s):  Department of Cardiology, Peking University First Hospital, Peking University, Beijing 100043, China

Corresponding email(s):   muhtebar@hotmail.com, huoyong@263.net.cn

Key Words:  Acute myocardial infarction (AMI), Percutaneous coronary intervention (PCI), Renal function, Estimated glomerular filtration rate (eGFR), Mortality


Jian-ping Li, Mohetaboer Momin, Yong Huo, Chun-yan Wang, Yan Zhang, Yan-jun Gong, Zhao-ping Liu, Xin-gang Wang, Bo Zheng. Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention[J]. Journal of Zhejiang University Science B, 2012, 13(8): 638-644.

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author="Jian-ping Li, Mohetaboer Momin, Yong Huo, Chun-yan Wang, Yan Zhang, Yan-jun Gong, Zhao-ping Liu, Xin-gang Wang, Bo Zheng",
journal="Journal of Zhejiang University Science B",
volume="13",
number="8",
pages="638-644",
year="2012",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1201005"
}

%0 Journal Article
%T Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention
%A Jian-ping Li
%A Mohetaboer Momin
%A Yong Huo
%A Chun-yan Wang
%A Yan Zhang
%A Yan-jun Gong
%A Zhao-ping Liu
%A Xin-gang Wang
%A Bo Zheng
%J Journal of Zhejiang University SCIENCE B
%V 13
%N 8
%P 638-644
%@ 1673-1581
%D 2012
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1201005

TY - JOUR
T1 - Renal insufficiency is an independent predictor of in-hospital mortality for patients with acute myocardial infarction receiving primary percutaneous coronary intervention
A1 - Jian-ping Li
A1 - Mohetaboer Momin
A1 - Yong Huo
A1 - Chun-yan Wang
A1 - Yan Zhang
A1 - Yan-jun Gong
A1 - Zhao-ping Liu
A1 - Xin-gang Wang
A1 - Bo Zheng
J0 - Journal of Zhejiang University Science B
VL - 13
IS - 8
SP - 638
EP - 644
%@ 1673-1581
Y1 - 2012
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1201005


Abstract: 
Objective: To investigate the relationship between renal function and clinical outcomes among patients with acute ST-segment elevation myocardial infarction (ASTEMI), who were treated with emergency percutaneous coronary intervention (PCI). Methods: 420 patients hospitalized in Peking University First Hospital, diagnosed with ASTEMI treated with emergency (PCI) from January 2001 to June 2011 were enrolled in this study. estimated glomerular filtration rate (eGFR) was used as a measure of renal function. We compared the clinical parameters and outcomes between ASTEMI patients combined renal insufficiency and the patients with normal renal function. Results: There was a significant increase in the concentrations of fibrinogen and D-Dimer (P<0.05) and a much higher morbidity of diabetes mellitus in the group of patients with chronic kidney disease (CKD; eGFR<60 ml/(min·1.73 m2)) (P<0.01). CKD (eGFR<60 ml/(min·1.73 m2)) was an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI receiving PCI therapy rapidly (P=0.032, odds ratio (OR) 4.159, 95% confidence interval (CI) 1.127–15.346). Conclusions: Renal insufficiency is an independent predictor of in-hospital mortality for patients hospitalized with ASTEMI treated with primary PCI.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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