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CLC number: R541.4

On-line Access: 2013-07-30

Received: 2013-06-18

Revision Accepted: 2013-07-05

Crosschecked: 2013-07-19

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Journal of Zhejiang University SCIENCE B 2013 Vol.14 No.8 P.664-669


Interleukin-17 and acute coronary syndrome

Author(s):  Sheng-an Su, Hong Ma, Li Shen, Mei-xiang Xiang, Jian-an Wang

Affiliation(s):  Cardiovascular Key Lab of Zhejiang Province, Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   xiangmx@yahoo.com

Key Words:  Interleukin-17, Acute coronary syndrome, Atherosclerosis, Inflammation

Sheng-an Su, Hong Ma, Li Shen, Mei-xiang Xiang, Jian-an Wang. Interleukin-17 and acute coronary syndrome[J]. Journal of Zhejiang University Science B, 2013, 14(8): 664-669.

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author="Sheng-an Su, Hong Ma, Li Shen, Mei-xiang Xiang, Jian-an Wang",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Interleukin-17 and acute coronary syndrome
%A Sheng-an Su
%A Hong Ma
%A Li Shen
%A Mei-xiang Xiang
%A Jian-an Wang
%J Journal of Zhejiang University SCIENCE B
%V 14
%N 8
%P 664-669
%@ 1673-1581
%D 2013
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.BQICC701

T1 - Interleukin-17 and acute coronary syndrome
A1 - Sheng-an Su
A1 - Hong Ma
A1 - Li Shen
A1 - Mei-xiang Xiang
A1 - Jian-an Wang
J0 - Journal of Zhejiang University Science B
VL - 14
IS - 8
SP - 664
EP - 669
%@ 1673-1581
Y1 - 2013
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.BQICC701

inflammation plays an important role in atherosclerosis, which is also crucial for acute coronary syndrome (ACS). Recent studies have revealed that interleukin (IL)-17, which was regarded as a pro-inflammatory cytokine, has a dual function in the progress of ACS. In this review, we sum up both experimental and clinical studies on the relevance of IL-17 to atherosclerosis and its complications, and summarize the research progress on the effect of IL-17 on the atherosclerotic plaque stability and ACS onset. Although the studies are controversial and the mechanism remains unclear, we highlight the knowledge of the role of IL-17 in ACS and elucidate its potential mechanism.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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