CLC number: B845
On-line Access: 2018-08-02
Received: 2017-09-21
Revision Accepted: 2017-12-04
Crosschecked: 2018-07-06
Cited: 0
Clicked: 3289
Shao-wei Xue, Tien-wen Lee, Yong-hu Guo. Spontaneous activity in medial orbitofrontal cortex correlates with trait anxiety in healthy male adults[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B1700481 @article{title="Spontaneous activity in medial orbitofrontal cortex correlates with trait anxiety in healthy male adults", %0 Journal Article TY - JOUR
成年男性特质型焦虑与内侧眶额的自发活动有关创新点:采用Louvain网络模块检测方法对大脑内侧眶额进行自动化功能亚区分割,并发现内侧眶额与健康成年男性特质型焦虑的关系. 方法:采用静息态低频振幅比率(fALFF)、静息态功能连通性(RSFC)和脑区功能亚区自动化分割方法. 结论:成年男性特质型焦虑分数与内侧眶额的fALFF指标间存在显著相关性,并与右脑内侧眶额和楔前叶之间的功能连通性有关.因此,可以认为内侧眶额涉及特质型焦虑加工. 关键词组: Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article
Reference[1]Banks SJ, Eddy KT, Angstadt M, et al., 2007. Amygdala-frontal connectivity during emotion regulation. Soc Cogn Affect Neurosci, 2(4):303-312. [2]Biswal B, Yetkin FZ, Haughton VM, et al., 1995. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med, 34(4):537-541. [3]Biswal BB, van Kylen J, Hyde JS, 1997. Simultaneous assessment of flow and BOLD signals in resting-state functional connectivity maps. NMR Biomed, 10(4-5):165-170. [4]Blair J, Mitchell D, Blair K, 2005. The Psychopath: Emotion and the Brain. Blackwell Publishing, Oxford, p.81-86. [5]Blair RJR, 2007. Dysfunctions of medial and lateral orbitofrontal cortex in psychopathy. Ann NY Acad Sci, 1121(1):461-479. [6]Buckner RL, Andrews-Hanna JR, Schacter DL, 2008. The brain’s default network: anatomy, function, and relevance to disease. Ann NY Acad Sci, 1124(1):1-38. [7]Bystritsky A, Pontillo D, Powers M, et al., 2001. Functional MRI changes during panic anticipation and imagery exposure. Neuroreport, 12(18):3953-3957. [8]Chambers JA, Power KG, Durham RC, 2004. The relationship between trait vulnerability and anxiety and depressive diagnoses at long-term follow-up of generalized anxiety disorder. J Anxiety Disord, 18(5):587-607. [9]Foti NJ, Hughes JM, Rockmore DN, 2011. Nonparametric sparsification of complex multiscale networks. PLoS ONE, 6(2):e16431. [10]Fox MD, Raichle ME, 2007. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci, 8(9):700-711. [11]Gawda B, Szepietowska E, 2016. Trait anxiety modulates brain activity during performance of verbal fluency tasks. Front Behav Neurosci, 10:10. [12]Grachev ID, Apkarian AV, 2000. Anxiety in healthy humans is associated with orbital frontal chemistry. Mol Psychiatry, 5(5):482-488. [13]Greicius MD, Krasnow B, Reiss AL, et al., 2003. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA, 100(1):253-258. [14]Hahn A, Stein P, Windischberger C, et al., 2011. Reduced resting-state functional connectivity between amygdala and orbitofrontal cortex in social anxiety disorder. Neuroimage, 56(3):881-889. [15]Hakamata Y, Matsuoka Y, Inagaki M, et al., 2007. Structure of orbitofrontal cortex and its longitudinal course in cancer-related post-traumatic stress disorder. Neurosci Res, 59(4):383-389. [16]Hamm LL, Jacobs RH, Johnson MW, et al., 2014. Aberrant amygdala functional connectivity at rest in pediatric anxiety disorders. Biol Mood Anxiety Disord, 4(1):15. [17]Heekeren HR, Wartenburger I, Marschner A, et al., 2007. Role of ventral striatum in reward-based decision making. Neuroreport, 18(10):951-955. [18]Hoptman MJ, Zuo XN, Butler PD, et al., 2010. Amplitude of low-frequency oscillations in schizophrenia: a resting state fMRI study. Schizophr Res, 117(1):13-20. [19]Ieong HFH, Yuan Z, 2017. Abnormal resting-state functional connectivity in the orbitofrontal cortex of heroin users and its relationship with anxiety: a pilot fNIRS study. Sci Rep, 7:46522. [20]Kahnt T, Chang LJ, Park SQ, et al., 2012. Connectivity-based parcellation of the human orbitofrontal cortex. J Neurosci, 32(18):6240-6250. [21]Kent JM, Coplan JD, Mawlawi O, et al., 2005. Prediction of panic response to a respiratory stimulant by reduced orbitofrontal cerebral blood flow in panic disorder. Am J Psychiatry, 162(7):1379-1381. [22]Kim MJ, Gee DG, Loucks RA, et al., 2011. Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest. Cereb Cortex, 21(7):1667-1673. [23]Kim MJ, Brown AC, Mattek AM, et al., 2016. The inverse relationship between the microstructural variability of amygdala-prefrontal pathways and trait anxiety is moderated by sex. Front Syst Neurosci, 10:93. [24]Lai CH, Wu YT, 2015. The patterns of fractional amplitude of low-frequency fluctuations in depression patients: the dissociation between temporal regions and fronto-parietal regions. J Affect Disord, 175:441-445. [25]Liao W, Qiu CJ, Gentili C, et al., 2010. Altered effective connectivity network of the amygdala in social anxiety disorder: a resting-state fMRI study. PLoS ONE, 5(12):e15238. [26]Liu HG, Qin W, Qi HT, et al., 2015. Parcellation of the human orbitofrontal cortex based on gray matter volume covariance. Hum Brain Mapp, 36(2):538-548. [27]Maddock RJ, Garrett AS, Buonocore MH, 2003. Posterior cingulate cortex activation by emotional words: fMRI evidence from a valence decision task. Hum Brain Mapp, 18(1):30-41. [28]Milad MR, Rauch SL, 2007. The role of the orbitofrontal cortex in anxiety disorders. Ann NY Acad Sci, 1121(1):546-561. [29]Milad MR, Rauch SL, Pitman RK, et al., 2006. Fear extinction in rats: implications for human brain imaging and anxiety disorders. Biol Psychol, 73(1):61-71. [30]Newman MEJ, 2006. Modularity and community structure in networks. Proc Natl Acad Sci USA, 103(23):8577-8582. [31]Nooner KB, Colcombe SJ, Tobe RH, et al., 2012. The NKI-Rockland Sample: a model for accelerating the pace of discovery science in psychiatry. Front Neurosci, 6:152. [32]Power JD, Barnes KA, Snyder AZ, et al., 2012. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage, 59(3):2142-2154. [33]Qiu CJ, Feng Y, Meng YJ, et al., 2015. Analysis of altered baseline brain activity in drug-naive adult patients with social anxiety disorder using resting-state functional MRI. Psychiatry Investig, 12(3):372-380. [34]Raichle ME, MacLeod AM, Snyder AZ, et al., 2001. A default mode of brain function. Proc Natl Acad Sci USA, 98(2):676-682. [35]Raymond JG, Steele JD, Seriès P, 2017. Modeling trait anxiety: from computational processes to personality. Front Psychiatry, 8:1. [36]Scheinost D, Stoica T, Saksa J, et al., 2013. Orbitofrontal cortex neurofeedback produces lasting changes in contamination anxiety and resting-state connectivity. Transl Psychiatry, 3(4):e250. [37]Shiba Y, Santangelo AM, Roberts AC, 2016. Beyond the medial regions of prefrontal cortex in the regulation of fear and anxiety. Front Syst Neurosci, 10:12. [38]Shin LM, Liberzon I, 2010. The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology, 35(1):169-191. [39]Spampinato MV, Wood JN, de Simone V, et al., 2009. Neural correlates of anxiety in healthy volunteers: a voxel-based morphometry study. J Neuropsychiatry Clin Neurosci, 21(2):199-205. [40]Spielberger CD, Gorsuch RL, Lushene RE, 1983. Manual for the State-Trait Anxiety Inventory. Consulting Psychologists Press, Palo Alto, USA. [41]Tian X, Wei DT, Du X, et al., 2016. Assessment of trait anxiety and prediction of changes in state anxiety using functional brain imaging: a test–retest study. NeuroImage, 133:408-416. [42]Tzourio-Mazoyer N, Landeau B, Papathanassiou D, et al., 2002. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage, 15(1):273-289. [43]Wang S, Xu X, Zhou M, et al., 2017. Hope and the brain: trait hope mediates the protective role of medial orbitofrontal cortex spontaneous activity against anxiety. Neuroimage, 157:439-447. [44]Wang ZQ, Xia MR, Dai ZJ, et al., 2015. Differentially disrupted functional connectivity of the subregions of the inferior parietal lobule in Alzheimer’s disease. Brain Struct Funct, 220(2):745-762. [45]Worsley K, 2001. Statistical analysis of activation images. In: Jezzard P, Matthews PM, Smith SM (Eds.), Functional MRI: an Introduction to Methods. Oxford University Press, New York, USA, p.251-270. [46]Xia MR, Wang ZQ, Dai ZJ, et al., 2014. Differentially disrupted functional connectivity in posteromedial cortical subregions in Alzheimer’s disease. J Alzheimers Dis, 39(3):527-543. [47]Yan CG, Zang YF, 2010. DPARSF: a MATLAB toolbox for “pipeline” data analysis of resting-state fMRI. Front Syst Neurosci, 4:13. [48]Zang YF, He Y, Zhu CZ, et al., 2007. Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev, 29(2):83-91. [49]Zhang DY, Raichle ME, 2010. Disease and the brain’s dark energy. Nat Rev Neurol, 6(1):15-28. [50]Zhao XH, Wang PJ, Li CB, et al., 2007. Altered default mode network activity in patient with anxiety disorders: an fMRI study. Eur J Radiol, 63(3):373-378. [51]Zou QH, Zhu CZ, Yang YH, et al., 2008. An improved approach to detection of amplitude of low-frequency fluctuation (ALFF) for resting-state fMRI: fractional ALFF. J Neurosci Methods, 172(1):137-141. [52]Zuo XN, di Martino A, Kelly C, et al., 2010. The oscillating brain: complex and reliable. Neuroimage, 49(2):1432-1445. Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou
310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE |
Open peer comments: Debate/Discuss/Question/Opinion
<1>