CLC number: R511
On-line Access: 2020-12-09
Received: 2020-04-17
Revision Accepted: 2020-10-22
Crosschecked: 2020-11-11
Cited: 0
Clicked: 2846
Yong-zheng Guo, Kai-jin Xu, Yong-tao Li, Jia-dan Fu, Min Xu, Ling Yu, Ji-fang Sheng, Biao Zhu. Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2000204 @article{title="Safety of protease inhibitors and Arbidol for SARS-CoV-2 pneumonia in Zhejiang Province, China", %0 Journal Article TY - JOUR
蛋白酶抑制剂联合阿比多尔的抗病毒方案在浙江省SARS-CoV-2肺炎患者中的安全性研究创新点:首次评价了蛋白酶抑制剂联合阿比多尔的抗病毒方案在SARS-CoV-2肺炎患者中安全性良好. 方法:回顾性分析了52例SARS-CoV-2肺炎患者的临床资料,分析患者入院时以及抗病毒治疗期间症状、肝功能及血脂水平等的变化. 结论:该方案最常见的不良反应为消化道症状和血脂代谢异常,血清甘油三酯、总胆固醇和低密度脂蛋白胆固醇水平均较治疗前显著升高;与洛匹那韦/利托那韦相比,达芦那韦/考比司他对血脂代谢的负面影响较小;建议对使用蛋白酶抑制剂联合阿比多尔抗病毒方案的患者密切监测和随访血脂水平变化. 关键词组: Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article
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