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Bio-Design and Manufacturing  2023 Vol.6 No.1 P.26-37

http://doi.org/10.1007/s42242-022-00214-2


Design, fabrication, and structural safety validation of 3D-printable biporous bone augments


Author(s):  Yeokyung Kang, Dasol Lim, Doo-Hoon Sun, Jong-Chul Park & Jungsung Kim

Affiliation(s):  Central Research & Development Center, Corentec Company Ltd., 33-2, Banpo-daero 20-gil, Seocho-gu, Seoul, Republic of Korea; more

Corresponding email(s):   jskim@corentec.com

Key Words:  Bone augment, 3D printing, Biporous structure, Total hip arthroplasty, Metal implant


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Yeokyung Kang, Dasol Lim, Doo-Hoon Sun, Jong-Chul Park & Jungsung Kim. Design, fabrication, and structural safety validation of 3D-printable biporous bone augments[J]. Journal of Zhejiang University Science D, 2023, 6(1): 26-37.

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Abstract: 
The use of commercial products such as a cup and liner for total hip arthroplasty for patients with severe bone defects has a high probability of failure. In these patients the cup alone cannot cover the bone defect, and thus, an additional augment or cage is required. In this study, we designed three-dimensional (3D) printable bone augments as an alternative to surgeries using reinforcement cages. Thirty-five sharp-edged bone augments of various sizes were 3D printed. A biporous structure was designed to reduce the weight of the augment and to facilitate bone ingrowth. Two types of frames were used to prevent damage to the augments porous structure and maintain its stability during printing. Furthermore, two types of holes were provided for easy augment fixation at various angles. Fatigue tests were performed on a combination of worst-case sizes derived using finite element analysis. The test results confirmed the structural stability of the specimens at a load of 5340 N. Although the porosity of the specimens was measured to be 63.70%, it cannot be said that the porous nature was uniformly distributed because porosity tests were performed locally and randomly. In summary, 3D-printable biporous bone augments capable of bonding from various angles and bidirectionally through angulation and bottom-plane screw holes are proposed. The mechanical results with bone augments indicate good structural safety in patients. However, further research is necessary to study the clinical applications of the proposed bone augment.

韩国Jungsung Kim等 | 可三维打印的双孔结构骨增量装置的设计、制造和结构安全性验证

本研究论文设计、制造了一种新型骨增量装置并对其进行安全性验证。对于有严重骨缺损的患者,使用商业产品如髋臼杯和衬垫进行全髋关节置换手术,失败的可能性很大。对于这些患者,单靠髋臼杯不能覆盖骨缺损处,因此需要额外的骨增量装置或固定支架。本研究设计了可三维(3D)打印的骨增量装置,作为使用固定支架手术的替代方案。该增量装置具有双孔结构,以减轻整体重量并促进骨生长,同时利用两种框架来防止对多孔结构的损害,并在打印过程中保持整体稳定性。此外还设计了两种类型的孔,以便在不同角度固定假体。本研究3D打印了35个不同大小的具有尖锐边缘的骨增量装置,并对有限元分析结果最不理想的试样进行疲劳测试,结果证实了试样在5340 N载荷下的结构稳定性。在实验中测得试样的孔隙率为63.70%,但孔隙率测试是局部随机进行的,因此不能证明孔隙率是均匀分布的。综上所述,本研究提出了能够通过成角螺丝孔和底面螺丝孔双向和不同角度进行连接的3D打印双孔骨增量装置。该装置的力学试验结果表明其结构安全性良好。然而,更深入的研究该装置的临床应用依然是必要的。

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