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Received: 2005-07-02

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Journal of Zhejiang University SCIENCE B 2005 Vol.6 No.9 P.853~858

10.1631/jzus.2005.B0853


Application of new tissue microarrayer−ZM-1 without recipient paraffin block


Author(s):  MENG Pan-qing, HOU Gang, ZHOU Gui-ying, PENG Jia-ping, DONG Qi, ZHENG Shu

Affiliation(s):  Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; more

Corresponding email(s):   zhengshu@zju.edu.cn

Key Words:  Tissue microarray (TMA), Construction technique, Method


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MENG Pan-qing, HOU Gang, ZHOU Gui-ying, PENG Jia-ping, DONG Qi, ZHENG Shu. Application of new tissue microarrayer−ZM-1 without recipient paraffin block[J]. Journal of Zhejiang University Science B, 2005, 6(9): 853~858.

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author="MENG Pan-qing, HOU Gang, ZHOU Gui-ying, PENG Jia-ping, DONG Qi, ZHENG Shu",
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volume="6",
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doi="10.1631/jzus.2005.B0853"
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%A MENG Pan-qing
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%A ZHOU Gui-ying
%A PENG Jia-ping
%A DONG Qi
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A1 - MENG Pan-qing
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A1 - ZHOU Gui-ying
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A1 - DONG Qi
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DOI - 10.1631/jzus.2005.B0853


Abstract: 
The ZM-1 tissue microarrayer designed by our groups is manufactured in stainless steel and brass and contains many features that make TMA (tissue microarray) paraffin blocks construction faster and more convenient. By means of ZM-1 tissue microarrayer, biopsy needles are used to punch the donor tissue specimens respectively. All the needles with the punched specimen cylinders are arrayed into the array-board, with an array of small holes dug to fit the needles. All the specimen cylinders arraying and the TMA paraffin block shaping are finished in only one step so that the specimen cylinders and the paraffin of the TMA block can very easily be incorporated and the recipient paraffin blocks need not be made in advance, and the paraffin used is the same as that for conventional pathology purpose. ZM-1 tissue microarrayer is easy to be manufactured, does not need any precision location system, and so is much cheaper than the currently used instrument. Our method’s relatively cheap and simple ZM-1 tissue microarrayer technique of constructing TMA paraffin block may facilitate popularization of the TMA technology.

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