JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Non-specific anti-viral approach towards Ebola virus infection: a comment on �Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis�

Author(s): Beuy Joob, Viroj Wiwanitkit
Affiliation(s): Sanitation 1 Medical Academic Center, Bangkok 10160, Thailand; more
Corresponding email(s): wviroj@yahoo.com
Key Words: Ebola, Non-specific anti-viral

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Beuy Joob, Viroj Wiwanitkit. Non-specific anti-viral approach towards Ebola virus infection: a comment on �Against Ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis�[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B1500035

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%A Beuy Joob
%A Viroj Wiwanitkit
%J Journal of Zhejiang University SCIENCE B
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PB - Zhejiang University Press & Springer
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doi="https://doi.org/10.1631/jzus.B1500035"

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: The recent "Viewpoint" by Zhang et al. (2015) entitled "Against ebola: type I interferon guard risk and mesenchymal stromal cell combat sepsis", pub-lished in Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), is very interesting, which mentioned the possible role of non-specific anti-viral approach towards ebola virus infection. They noted the role of interferon and "applying a non-specific anti-viral approach during the incubation period of virus infection as an essential protection to put the host's immune system into an alert state and henceforth to slow down the viral replication." In previous report, Zhang and Wang (2014) mentioned the long history of ebola virus infection discovery. However, the success in disease management is still not reached. Indeed, the role of interferon in treatment of ebola has been widely discussed (Shuchman, 2014). The effectiveness of interferon has been proved in some animal models (Smith et al., 2013).

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Reference

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