JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma

Author(s): Taifeng ZHU^1, Jiali XING^2, Ziyue HUANG¹, Shanshan WANG¹, Duo LI¹, Xinting SANG¹, Cong NING¹, Chengpei ZHU³, Yongchang ZHENG¹, Haitao ZHAO¹
Affiliation(s): ¹Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing 100730, China ²State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), Beijing 100730, China ³Department of General Surgery Center, Beijing Youan Hospital, Clinical Center for Liver Cancer, Capital Medical University, Beijing 100069, China
Corresponding email(s): Haitao ZHAO, zhaoht@pumch.cn Yongchang ZHENG, zhengyongchang@pumch.cn
Key Words: Cholangiocarcinoma; Bile; Omics; Diagnosis

Share this article to： More <<< Previous Paper \|Next Paper >>>

Taifeng ZHU^1*, Jiali XING^2*, Ziyue HUANG¹, Shanshan WANG¹, Duo LI¹, Xinting SANG¹, Cong NING¹, Chengpei ZHU³, Yongchang ZHENG¹, Haitao ZHAO¹. Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2500181

@article{title="Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma",
author="Taifeng ZHU^1*, Jiali XING^2*, Ziyue HUANG¹, Shanshan WANG¹, Duo LI¹, Xinting SANG¹, Cong NING¹, Chengpei ZHU³, Yongchang ZHENG¹, Haitao ZHAO¹",
journal="Journal of Zhejiang University Science B",
year="in press",
publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.B2500181"
}

%0 Journal Article
%T Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma
%A Taifeng ZHU^1*
%A Jiali XING^2*
%A Ziyue HUANG¹
%A Shanshan WANG¹
%A Duo LI¹
%A Xinting SANG¹
%A Cong NING¹
%A Chengpei ZHU³
%A Yongchang ZHENG¹
%A Haitao ZHAO¹
%J Journal of Zhejiang University SCIENCE B
%P
%@ 1673-1581
%D in press
%I Zhejiang University Press & Springer
doi="https://doi.org/10.1631/jzus.B2500181"

TY - JOUR
T1 - Applications and advances of bile-based omics technologies in the diagnosis of cholangiocarcinoma
A1 - Taifeng ZHU^1*
A1 - Jiali XING^2*
A1 - Ziyue HUANG¹
A1 - Shanshan WANG¹
A1 - Duo LI¹
A1 - Xinting SANG¹
A1 - Cong NING¹
A1 - Chengpei ZHU³
A1 - Yongchang ZHENG¹
A1 - Haitao ZHAO¹
J0 - Journal of Zhejiang University Science B
SP -
EP -
%@ 1673-1581
Y1 - in press
PB - Zhejiang University Press & Springer
ER -
doi="https://doi.org/10.1631/jzus.B2500181"

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: Cholangiocarcinoma (CCA) is challenging to diagnose due to its subtle symptoms and the limited sensitivity and specificity of conventional diagnostic modalities. Therefore, there is an urgent need for more effective detection strategies. Bile, a fluid directly secreted by the biliary system, offers a unique advantage in the diagnosis of CCA by providing a more precise representation of tumor-associated molecules, coupled with its relative ease of collection. The rapid advancement of omics technologies has significantly facilitated the investigation of bile samples. This review explores the applications and advancements of bile-based omics in the diagnosis of CCA from multiple perspectives, including genomics, epigenomics, transcriptomics, proteomics, metabolomics, and microbiomics, aiming to provide new theoretical foundations and technical support for the diagnosis of this malignancy.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

Open peer comments: Debate/Discuss/Question/Opinion

<1>

- Go to

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference