CLC number: R562.25
On-line Access: 2018-09-04
Received: 2017-07-07
Revision Accepted: 2018-01-25
Crosschecked: 2018-08-07
Cited: 0
Clicked: 9955
Citations: Bibtex RefMan EndNote GB/T7714
Sheng-tao Zhao, Chang-zheng Wang. Regulatory T cells and asthma[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B1700346 @article{title="Regulatory T cells and asthma", %0 Journal Article TY - JOUR
调节性T细胞与哮喘关键词组: Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article
Reference[1]Abbas AK, Benoist C, Bluestone JA, et al., 2013. Regulatory T cells: recommendations to simplify the nomenclature. Nat Immunol, 14(4):307-308. [2]Albert MH, Liu Y, Anasetti C, et al., 2005. Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation. Eur J Immunol, 35(9):2598-2607. [3]Baatjes AJ, Smith SG, Watson R, et al., 2015. T regulatory cell phenotypes in peripheral blood and bronchoalveolar lavage from non-asthmatic and asthmatic subjects. Clin Exp Allergy, 45(11):1654-1662. [4]Bardel E, Larousserie F, Charlot-Rabiega P, et al., 2008. Human CD4+CD25+Foxp3+ regulatory T cells do not constitutively express IL-35. J Immunol, 181(10):6898-6905. [5]Berker M, Frank LJ, Gessner AL, et al., 2017. Allergies-A T cells perspective in the era beyond the TH1/TH2 paradigm. Clin Immunol, 174:73-83. [6]Burks AW, Calderon MA, Casale T, et al., 2013. Update on allergy immunotherapy: American Academy of Allergy, Asthma & Immunology/European Academy of Allergy and Clinical Immunology/PRACTALL consensus report. J Allergy Clin Immunol, 131(5):1288-1296.e3. [7]Charbonnier LM, Wang S, Georgiev P, et al., 2015a. Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. Nat Immunol, 16(11):1162-1173. [8]Charbonnier LM, Janssen E, Chou J, et al., 2015b. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA. J Allergy Clin Immunol, 135(1):217-227.e9. [9]Collison LW, Workman CJ, Kuo TT, et al., 2007. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature, 450(7169):566-569. [10]Deaglio S, Robson SC, 2011. Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity. Adv Pharmacol, 61:301-332. [11]Deaglio S, Dwyer KM, Gao WD, et al., 2007. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med, 204(6):1257-1265. [12]Delgoffe GM, Woo SR, Turnis ME, et al., 2013. Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis. Nature, 501(7466):252-256. [13]Desreumaux P, Foussat A, Allez M, et al., 2012. Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn’s disease. Gastroenterology, 143(5):1207-1217.e2. [14]Fu CL, Chuang YH, Chau LY, et al., 2006. Effects of adenovirus-expressing IL-10 in alleviating airway inflammation in asthma. J Gene Med, 8(12):1393-1399. [15]Gambineri E, Torgerson TR, Ochs HD, 2003. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol, 15(4):430-435. [16]Gondek DC, Lu LF, Quezada SA, et al., 2005. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol, 174(4):1783-1786. [17]Grossman WJ, Verbsky JW, Barchet W, et al., 2004. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity, 21(4):589-601. [18]Hansen G, McIntire JJ, Yeung VP, et al., 2000. CD4+ T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J Clin Invest, 105(1):61-70. [19]Hartl D, Koller B, Mehlhorn AT, et al., 2007. Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma. J Allergy Clin Immunol, 119(5):1258-1266. [20]Heederik D, von Mutius E, 2012. Does diversity of environmental microbial exposure matter for the occurrence of allergy and asthma? J Allergy Clin Immunol, 130(1):44-50. [21]Hershey GK, Friedrich MF, Esswein LA, et al., 1997. The association of atopy with a gain-of-function mutation in the α subunit of the interleukin-4 receptor. N Engl J Med, 337(24):1720-1725. [22]Jethwa H, Adami AA, Maher J, 2014. Use of gene-modified regulatory T-cells to control autoimmune and alloimmune pathology: is now the right time? Clin Immunol, 150(1):51-63. [23]Jiang YQ, Zhao ST, Yang X, et al., 2015. Dll4 in the DCs isolated from OVA-sensitized mice is involved in Th17 differentiation inhibition by 1,25-dihydroxyvitamin D3 in vitro. J Asthma, 52(10):989-995. [24]Joetham A, Schedel M, O'Connor BP, et al., 2017. Inducible and naturally occurring regulatory T cells enhance lung allergic responses through divergent transcriptional pathways. J Allergy Clin Immunol, 139(4):1331-1342. [25]John M, Lim S, Seybold J, et al., 1998. Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1α, granulocyte-macrophage colony-stimulating factor, and interferon-γ release from alveolar macrophages in asthma. Am J Respir Crit Care Med, 157(1):256-262. [26]Jordan MS, Boesteanu A, Reed AJ, et al., 2001. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol, 2(4):301-306. [27]Kanamori M, Nakatsukasa H, Okada M, et al., 2016. Induced regulatory T cells: their development, stability, and applications. Trends Immunol, 37(11):803-811. [28]Kitani A, Fuss I, Nakamura K, et al., 2003. Transforming growth factor (TGF)-β1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-β1-mediated fibrosis. J Exp Med, 198(8):1179-1188. [29]Klatka M, Kaszubowska L, Grywalska E, et al., 2014. Treatment of Graves’ disease with methimazole in children alters the proliferation of Treg cells and CD3+ T lymphocytes. Folia Histochem Cytobiol, 52(1):69-77. [30]Koch MA, Thomas KR, Perdue NR, et al., 2012. T-bet+ Treg cells undergo abortive Th1 cell differentiation due to impaired expression of IL-12 receptor β2. Immunity, 37(3):501-510. [31]Komatsu N, Mariotti-Ferrandiz ME, Wang Y, et al., 2009. Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci USA, 106(6):1903-1908. [32]Komatsu N, Okamoto K, Sawa S, et al., 2014. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med, 20(1):62-68. [33]Krishnamoorthy N, Khare A, Oriss TB, et al., 2012. Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthma. Nat Med, 18(10):1525-1530. [34]Lapierre P, Béland K, Yang R, et al., 2013. Adoptive transfer of ex vivo expanded regulatory T cells in an autoimmune hepatitis murine model restores peripheral tolerance. Hepatology, 57(1):217-227. [35]Lewkowich IP, Herman NS, Schleifer KW, et al., 2005. CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J Exp Med, 202(11):1549-1561. [36]Liang BT, Workman C, Lee J, et al., 2008. Regulatory T cells inhibit dendritic cells by lymphocyte activation gene-3 engagement of MHC class II. J Immunol, 180(9):5916-5926. [37]Lu YJ, Wang JR, Gu J, et al., 2014. Rapamycin regulates iTreg function through CD39 and Runx1 pathways. J Immunol Res, 2014:989434. [38]Massoud AH, Charbonnier LM, Lopez D, et al., 2016. An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells. Nat Med, 22(9):1013-1022. [39]Mathias CB, Hobson SA, Garcia-Lloret M, et al., 2011. IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signaling. J Allergy Clin Immunol, 127(3):795-805.e6. [40]Melnik BC, John SM, Carrera-Bastos P, et al., 2016. Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation. Clin Transl Allergy, 6:18. [41]Miyara M, Yoshioka Y, Kitoh A, et al., 2009. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity, 30(6):899-911. [42]Nakamura K, Kitani A, Fuss I, et al., 2004. TGF-β1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J Immunol, 172(2):834-842. [43]Nakao A, Miike S, Hatano M, et al., 2000. Blockade of transforming growth factor β/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity. J Exp Med, 192(2):151-158. [44]Niedbala W, Wei XQ, Cai BL, et al., 2007. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. Eur J Immunol, 37(11):3021-3029. [45]Nieminen K, Laaksonen K, Savolainen J, 2009. Three-year follow-up study of allergen-induced in vitro cytokine and signalling lymphocytic activation molecule mRNA responses in peripheral blood mononuclear cells of allergic rhinitis patients undergoing specific immunotherapy. Int Arch Allergy Immunol, 150(4):370-376. [46]Noval Rivas M, Burton OT, Wise P, et al., 2015. Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergy. Immunity, 42(3):512-523. [47]Oh JW, Seroogy CM, Meyer EH, et al., 2002. CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J Allergy Clin Immunol, 110(3):460-468. [48]Ohnmacht C, Park JH, Cording S, et al., 2015. The microbiota regulates type 2 immunity through RORγt+ T cells. Science, 349(6251):989-993. [49]Olson BM, Sullivan JA, Burlingham WJ, 2013. Interleukin 35: a key mediator of suppression and the propagation of infectious tolerance. Front Immunol, 4:315. [50]Prinz I, Koenecke C, 2012. Therapeutic potential of induced and natural FoxP3+ regulatory T cells for the treatment of Graft-versus-host disease. Arch Immunol Ther Exp (Warsz), 60(3):183-190. [51]Read S, Malmström V, Powrie F, 2000. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J Exp Med, 192(2):295-302. [52]Reddel HK, Levy ML, 2015. The GINA asthma strategy report: what’s new for primary care? NPJ Prim Care Respir Med, 25:15050. [53]Rosa-Rosa L, Zimmermann N, Bernstein JA, et al., 1999. The R576 IL-4 receptor α allele correlates with asthma severity. J Allergy Clin Immunol, 104(5):1008-1014. [54]Round JL, Mazmanian SK, 2010. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci USA, 107(27):12204-12209. [55]Round JL, Lee SM, Li J, et al., 2011. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science, 332(6032):974-977. [56]Rudensky AY, 2011. Regulatory T cells and Foxp3. Immunol Rev, 241(1):260-268. [57]Sagoo P, Ali N, Garg G, et al., 2011. Human regulatory T cells with alloantigen specificity are more potent inhibitors of alloimmune skin graft damage than polyclonal regulatory T cells. Sci Transl Med, 3(83):83ra42. [58]Sakaguchi S, Wing K, Onishi Y, et al., 2009. Regulatory T cells: how do they suppress immune responses? Int Immunol, 21(10):1105-1111. [59]Sato H, Sasaki N, Minamitani K, et al., 2012. Higher dose of methimazole causes frequent adverse effects in the management of Graves’ disease in children and adolescents. J Pediatr Endocrinol Metab, 25(9-10):863-867. [60]Scottà C, Esposito M, Fazekasova H, et al., 2013. Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+ FOXP3+ T regulatory cell subpopulations. Haematologica, 98(8):1291-1299. [61]Sitkovsky M, Lukashev D, Deaglio S, et al., 2008. Adenosine A2A receptor antagonists: blockade of adenosinergic effects and T regulatory cells. Br J Pharmacol, 153(S1):S457-S464. [62]Smith PM, Howitt MR, Panikov N, et al., 2013. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science, 341(6145):569-573. [63]Stämpfli MR, Cwiartka M, Gajewska BU, et al., 1999. Interleukin-10 gene transfer to the airway regulates allergic mucosal sensitization in mice. Am J Respir Cell Mol Biol, 21(5):586-596. [64]Stanilov NS, Miteva L, Cirovski G, et al., 2016. Increased transforming growth factor β and interleukin 10 transcripts in peripheral blood mononuclear cells of colorectal cancer patients. Contemp Oncol, 20(6):458-462. [65]Stelmach I, Sobocińska A, Majak P, et al., 2012. Comparison of the long-term efficacy of 3- and 5-year house dust mite allergen immunotherapy. Ann Allergy Asthma Immunol, 109(4):274-278. [66]Suárez-Fueyo A, Ramos T, Galán A, et al., 2014. Grass tablet sublingual immunotherapy downregulates the TH2 cytokine response followed by regulatory T-cell generation. J Allergy Clin Immunol, 133(1):130-138.e2. [67]Swamy RS, Reshamwala N, Hunter T, et al., 2012. Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy. J Allergy Clin Immunol, 130(1):215-224.e7. [68]Tachdjian R, Mathias C, Al Khatib S, et al., 2009. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J Exp Med, 206(10):2191-2204. [69]Tachdjian R, Al Khatib S, Schwinglshackl A, et al., 2010. In vivo regulation of the allergic response by the IL-4 receptor α chain immunoreceptor tyrosine-based inhibitory motif. J Allergy Clin Immunol, 125(5):1128-1136.e8. [70]Thornton AM, Shevach EM, 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med, 188(2):287-296. [71]Wang L, Fan J, Chen SQ, et al., 2013. Graft-versus-host disease is enhanced by selective CD73 blockade in mice. PLoS ONE, 8(3):e58397. [72]Wills-Karp M, Santeliz J, Karp CL, 2001. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat Rev Immunol, 1(1):69-75. [73]Won HY, Hwang ES, 2016. Transcriptional modulation of regulatory T cell development by novel regulators NR4As. Arch Pharm Res, 39(11):1530-1536. [74]Xia MC, Viera-Hutchins L, Garcia-Lloret M, et al., 2015. Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade. J Allergy Clin Immunol, 136(2):441-453. [75]Yawn J, Lawrence LA, Carroll WW, et al., 2015. Vitamin D for the treatment of respiratory diseases: is it the end or just the beginning? J Steroid Biochem Mol Biol, 148:326-337. [76]Zheng Y, Chaudhry A, Kas A, et al., 2009. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses. Nature, 458(7236):351-356. [77]Zhou XY, Bailey-Bucktrout S, Jeker LT, et al., 2009. Plasticity of CD4+FoxP3+ T cells. Curr Opin Immunol, 21(3):281-285. Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou
310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE |
Open peer comments: Debate/Discuss/Question/Opinion
<1>