JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Initial chest CT findings in COVID-19: correlation with clinical features

Author(s): Zhu-jing Shen, Nan Lu, Lu-lu Gao, Jian Lv, Hua-fu Luo, Ji-feng Jiang, Chao Xu, Shi-ya Li, Ju-jiang Mao, Kai Li, Xiao-pei Xu, Bin Lin
Affiliation(s): Department of Radiology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; more
Corresponding email(s): zjdxlinbin@zju.edu.cn
Key Words: Coronavirus disease 2019 (COVID-19); Chest computed tomography (CT); Viral pneumonia; Lymphopenia

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Zhu-jing Shen, Nan Lu, Lu-lu Gao, Jian Lv, Hua-fu Luo, Ji-feng Jiang, Chao Xu, Shi-ya Li, Ju-jiang Mao, Kai Li, Xiao-pei Xu, Bin Lin. Initial chest CT findings in COVID-19: correlation with clinical features[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2000133

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author="Zhu-jing Shen, Nan Lu, Lu-lu Gao, Jian Lv, Hua-fu Luo, Ji-feng Jiang, Chao Xu, Shi-ya Li, Ju-jiang Mao, Kai Li, Xiao-pei Xu, Bin Lin",
journal="Journal of Zhejiang University Science B",
year="in press",
publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.B2000133"
}

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%A Zhu-jing Shen
%A Nan Lu
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%A Ji-feng Jiang
%A Chao Xu
%A Shi-ya Li
%A Ju-jiang Mao
%A Kai Li
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%A Bin Lin
%J Journal of Zhejiang University SCIENCE B
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A1 - Hua-fu Luo
A1 - Ji-feng Jiang
A1 - Chao Xu
A1 - Shi-ya Li
A1 - Ju-jiang Mao
A1 - Kai Li
A1 - Xiao-pei Xu
A1 - Bin Lin
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Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: In December 2019, coronavirus disease 2019 (COVID-19), a new de novo infectious disease, was first identified in Wuhan, China and quickly spread across China and around the world. The etiology was a novel betacoronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Lu et al., 2020). On Mar. 11, 2020, World Health Organization (WHO) characterized COVID-19 as a global pandemic. As of Mar. 22, 2020, over 292 000 confirmed COVID-19 cases have been reported globally. To date, COVID-19, with its high infectivity, has killed more people than severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) combined (Wu and McGoogan, 2020).

2019冠状病毒病首次胸部CT影像表现及其与临床表现的相关性研究

目的:分析2019冠状病毒病(COVID-19)患者首次胸部CT影像表现及其与临床表现(包括发热症状、实验室检查)的相关性.
创新点:初步探索COVID-19肺部病灶与临床数据的相关性,对评估COVID-19患者提供一定的依据.
方法:纳入2020年1月16日至2020年2月6日入院的36例COVID-19患者,回顾性分析首次胸部CT的影像学表现,包括影像特征、分布模式、累及范围等,并进一步分析其与临床特征(包括发病时间、发热症状、白细胞计数等)的相关性.
结论:结果发现,在自然病程中,COVID-19肺部病变与发病时间显著相关,特别是发热症状.COVID-19病变范围与淋巴细胞计数呈负相关,淋巴细胞减少可能是COVID-19进展的标志之一.
关键词组：2019冠状病毒病(COVID-19);胸部CT;发热;淋巴细胞减少

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[18]List of electronic supplementary materials

[19]Document S1 Supplementary materials

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2019冠状病毒病首次胸部CT影像表现及其与临床表现的相关性研究

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