CLC number: R735.9
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 2017-09-15
Cited: 0
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Wen-jie Lu, Hao-lei Cai, Ma-dong Ye, Yu-lian Wu, Bin Xu. Enucleation of non-invasive tumors in the proximal pancreas: indications and outcomes compared with standard resections[J]. Journal of Zhejiang University Science B, 2017, 18(10): 906-916.
@article{title="Enucleation of non-invasive tumors in the proximal pancreas: indications and outcomes compared with standard resections",
author="Wen-jie Lu, Hao-lei Cai, Ma-dong Ye, Yu-lian Wu, Bin Xu",
journal="Journal of Zhejiang University Science B",
volume="18",
number="10",
pages="906-916",
year="2017",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1600597"
}
%0 Journal Article
%T Enucleation of non-invasive tumors in the proximal pancreas: indications and outcomes compared with standard resections
%A Wen-jie Lu
%A Hao-lei Cai
%A Ma-dong Ye
%A Yu-lian Wu
%A Bin Xu
%J Journal of Zhejiang University SCIENCE B
%V 18
%N 10
%P 906-916
%@ 1673-1581
%D 2017
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600597
TY - JOUR
T1 - Enucleation of non-invasive tumors in the proximal pancreas: indications and outcomes compared with standard resections
A1 - Wen-jie Lu
A1 - Hao-lei Cai
A1 - Ma-dong Ye
A1 - Yu-lian Wu
A1 - Bin Xu
J0 - Journal of Zhejiang University Science B
VL - 18
IS - 10
SP - 906
EP - 916
%@ 1673-1581
Y1 - 2017
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1600597
Abstract: Objective: The aim of this study was to evaluate the safety and efficiency of enucleation (EU) for proximal pancreatic non-invasive neoplasms. Methods: Patients with solitary non-invasive neoplasms in the proximal pancreas from January 1998 to April 2014 at the Second Affiliated Hospital of Zhejiang University, Hangzhou, China were included. Different operations and outcomes were analyzed. Results: A total of 123 patients were enrolled. Forty patients (32.5%) underwent EU including 18 patients who had tumors close to the main pancreatic duct (MPD). Sixty-one patients (49.6%) had pancreaticoduodenectomy (PD) performed and 22 (17.9%) underwent central pancreatectomy (CP). Pathological outcomes included neuroendocrine tumors, cystic lesions, and solid pseudopapillary tumors. Operation time, intra-operative blood loss, and duration of hospital stay were significantly reduced in the EU group. PD was associated with the greatest complication rate (55.7%), followed by EU (50%) and CP (40.9%), though the pancreatic fistula rate after EU was the highest (50%), especially in patients with tumors larger than 3 cm and tumors close to the MPD. EU had advantages in the preservation of pancreatic parenchyma and endocrine and exocrine function. Conclusions: EU can be carried out safely and effectively for tumors in the proximal pancreas with improved outcomes compared with standard resections, even if the tumor is larger than 3 cm and close to the MPD.
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