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CLC number: R73

On-line Access: 2010-07-04

Received: 2009-11-24

Revision Accepted: 2010-03-12

Crosschecked: 2010-05-11

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Journal of Zhejiang University SCIENCE B 2010 Vol.11 No.7 P.542-546

10.1631/jzus.B0900378


Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature#


Author(s):  Hwa-chan Lee, Fen-fen Chen, Ching-chu Lo, Chung-jing Wang, Wei-chun Lo, Shi-ping Luh

Affiliation(s):  Department of Surgery, St. Martin de Porres Hospital, Chia-Yi City 60069, Taiwan, China, Department of Emergency Medicine, St. Martin de Porres Hospital, Chia-Yi City 60069, Taiwan, China, Department of Pathology, St. Martin de Porres Hospital, Chia-Yi City 60069, Taiwan, China, Department of Gastroenterology, St. Martin de Porres Hospital, Chia-Yi City 60069, Taiwan, China

Corresponding email(s):   luh572001@yahoo.com.tw

Key Words:  Gastric carcinoma, Thyroid metastasis, Lung metastasis


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Hwa-chan Lee, Fen-fen Chen, Ching-chu Lo, Chung-jing Wang, Wei-chun Lo, Shi-ping Luh. Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature#[J]. Journal of Zhejiang University Science B, 2010, 11(7): 542-546.

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author="Hwa-chan Lee, Fen-fen Chen, Ching-chu Lo, Chung-jing Wang, Wei-chun Lo, Shi-ping Luh",
journal="Journal of Zhejiang University Science B",
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pages="542-546",
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%A Shi-ping Luh
%J Journal of Zhejiang University SCIENCE B
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T1 - Metastasis of gastric carcinoma to the thyroid and lung: a case report and review of literature#
A1 - Hwa-chan Lee
A1 - Fen-fen Chen
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A1 - Chung-jing Wang
A1 - Wei-chun Lo
A1 - Shi-ping Luh
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SP - 542
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0900378


Abstract: 
Cancer metastasis to the thyroid is extremely rare. The more commonly reported primary sites for metastasis to the thyroid are the kidney, breast, lung, colon, esophagus, and uterus. thyroid metastasis from the stomach has only been reported in three cases. Herein, we report a 71-year-old man presenting with bilateral thyroid multinodular lesions. Bilateral near-total thyroidectomy was performed due to airway compression with related symptoms. Wedge resection of a suspicious pulmonary nodule, detected on CT, was performed for diagnosis. Polypoid lesions in the stomach were examined by trans-scopic biopsy. Poorly differentiated adenocarcinomas with the same histological profiles were noted at these three sites. The immunohistochemical staining for thyroglobulin of these specimens was negative. We conclude that a new thyroid mass appearing in a patient with present or prior malignancies should raise the concern of metastatic disease.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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