CLC number: R779.65
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 2018-02-07
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Wen-jia Xie, Ye-sheng Xu, Xia Zhang, Yu-feng Yao. Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty[J]. Journal of Zhejiang University Science B, 2018, 19(3): 218-226.
@article{title="Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty",
author="Wen-jia Xie, Ye-sheng Xu, Xia Zhang, Yu-feng Yao",
journal="Journal of Zhejiang University Science B",
volume="19",
number="3",
pages="218-226",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1700095"
}
%0 Journal Article
%T Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty
%A Wen-jia Xie
%A Ye-sheng Xu
%A Xia Zhang
%A Yu-feng Yao
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 3
%P 218-226
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1700095
TY - JOUR
T1 - Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty
A1 - Wen-jia Xie
A1 - Ye-sheng Xu
A1 - Xia Zhang
A1 - Yu-feng Yao
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 3
SP - 218
EP - 226
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1700095
Abstract: Objective: To assess the lower tear meniscus height (LTMH), central tear film thickness (CTFT), and central corneal epithelial thickness (CCET) after deep anterior lamellar keratoplasty (DALK). Methods: This was a retrospective cross-sectional study of 20 patients who had DALK in one eye over a three-month period. LTMH, CTFT, and CCET of the operated eyes and the unoperated fellow eyes were measured using high-definition optical coherence tomography (HD-OCT). Correlations between three OCT assessments and age, time following surgery, graft size, bed size, and the number of residual sutures were analyzed. Results: Compared to patients with keratoconus, patients with other corneal conditions had significantly higher CCET in the fellow eye (P=0.024). For all patients, CCET in the operated eye was significantly negatively correlated with the number of residual sutures (R=−0.579, P=0.008), and was significantly positively correlated with time following surgery (R=0.636, P=0.003). In the fellow eye, a significant positive correlation was found between age and CCET (R=0.551, P=0.012), and a significant negative correlation between age and CTFT (R=−0.491, P=0.028). LTMH was found to be significantly correlated between operated and fellow eyes (R=0.554, P=0.011). There was no significant correlation between LTMH and age, bed/graft size, time following surgery, or residual sutures (all possible correlations, P>0.05). Conclusions: Patients with keratoconus tend to have a thinner central corneal epithelium. Corneal epithelium keeps regenerating over time after DALK. DALK did not induce a significant change in tear volume compared with the fellow eye. Postoperative tear function might depend on an individual’s general condition, rather than on age, gender, bed/graft size, time following surgery, or residual sutures.
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