Full Text:   <396>

Summary:  <192>

CLC number: R246.3

On-line Access: 2018-11-02

Received: 2018-10-15

Revision Accepted: 2018-10-26

Crosschecked: 2018-10-26

Cited: 0

Clicked: 1167

Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Fan Qu

https://orcid.org/0000-0003-1851-1514

-   Go to

Article info.
Open peer comments

Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.11 P.815-817

http://doi.org/10.1631/jzus.B1801014


Towards a multidimensional scientific approach to improve clinical practices for infertility treatment


Author(s):  Yu-hang Zhu, Fan Qu

Affiliation(s):  Women’s Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China 2Institute for Women’s Health, University College London, London NW3 2PF, the United Kingdom

Corresponding email(s):   syqufan@zju.edu.cn

Key Words:  Multidimensional, Infertility treatment, Clinical practices


Share this article to: More |Next Article >>>

Yu-hang Zhu, Fan Qu. Towards a multidimensional scientific approach to improve clinical practices for infertility treatment[J]. Journal of Zhejiang University Science B, 2018, 19(11): 815-817.

@article{title="Towards a multidimensional scientific approach to improve clinical practices for infertility treatment",
author="Yu-hang Zhu, Fan Qu",
journal="Journal of Zhejiang University Science B",
volume="19",
number="11",
pages="815-817",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1801014"
}

%0 Journal Article
%T Towards a multidimensional scientific approach to improve clinical practices for infertility treatment
%A Yu-hang Zhu
%A Fan Qu
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 11
%P 815-817
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1801014

TY - JOUR
T1 - Towards a multidimensional scientific approach to improve clinical practices for infertility treatment
A1 - Yu-hang Zhu
A1 - Fan Qu
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 11
SP - 815
EP - 817
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1801014


Abstract: 
Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women, leading to infertility. However, there is no general agreement concerning how to diagnose and treat PCOS. The Rotterdam consensus statement from the European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine, the Chinese diagnostic criteria and consensus statement, and the clinical practice guideline from the Endocrine Society in the USA are widely recognized. Guidance has been provided for clinical practice based on a comparative analysis of the above three practice guidelines or consensus statements (Wang et al., 2018a). High body mass index (BMI) has no negative effect on the outcome of in vitro fertilization (IVF) in Chinese patients with PCOS; however, the conclusion may be limited by the retrospective design and potential bias (Pan et al., 2018). Neonatal birth weight is positively affected by both maternal pre-pregnancy body mass index (pre-BMI) and gestational weight gain (Du et al., 2017). Normal body weight is very important for conception. Women with PCOS are almost 3 times more likely to be obese than those without PCOS; however, no specific interventions are available to induce weight loss, and drugs are used to treat other symptoms of the syndrome or obesity in the general population. A network meta-analysis found that the amount of weight loss differed significantly according to the choice of drugs (in descending order):liraglutide, orlistat, and metformin. Liraglutide alone, liraglutide/metformin, and metformin alone significantly reduced waist circumference, but no change was found with orlistat, indicating liraglutide appears superior to the other drugs in reducing weight and waist circumference (Wang et al., 2018b). IVF, as a choice for more than 1 000 000 infertile couples each year, gives rise to the birth of over 3 000 000 babies worldwide.

通过多维度的科学方法提高不孕症治疗的临床实践水平

概要:不孕症正日渐成为一个重要的社会关切问题.中医及心理干预在不孕症的治疗,甚至提高子代健康水平等方面具有一定优势,但仍需更加规范及国际性的多中心临床研究来加强其有效临床治疗的循证基础.
关键词:多维度;不孕症;临床实践

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]Boukhris T, Sheehy O, Mottron L, et al., 2016. Antidepressant use during pregnancy and the risk of autism spectrum disorder in children. JAMA Pediatr, 170(2):117-124.

[2]Du MK, Ge LY, Zhou ML, et al., 2017. Effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 18(3):263-271.

[3]Frederiksen Y, Farver-Vestergaard I, Skovgård NG, et al., 2015. Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis. BMJ Open, 5(1):e006592.

[4]Lu YH, Wang N, Jin F, et al., 2013. Long-term follow-up of children conceived through assisted reproductive technology. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 14(5):359-371.

[5]Pan XM, Lin Z, Li N, et al., 2018. Effects of body mass index on the outcomes of in vitro fertilization in Chinese patients with polycystic ovary syndrome: a retrospective cohort study. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(6):490-496.

[6]Qu F, Wu Y, Hu XY, et al., 2016. The effects of acupuncture on polycystic ovary syndrome: a systematic review and meta-analysis. Eur J Integr Med, 8(1):12-18.

[7]Qu F, Wang FF, Wu Y, et al., 2017a. Transcutaneous electrical acupoint stimulation improves the outcomes of in vitro fertilization: a prospective, randomized and controlled study. Explore, 13(5):306-312.

[8]Qu F, Li R, Sun W, et al., 2017b. Use of electroacupuncture and transcutaneous electrical acupoint stimulation in reproductive medicine: a group consensus. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 18(3):186-193.

[9]Robinson N, 2017. Integrating acupuncture: are there positive health outcomes for women? J Zhejiang Univ-Sci B (Biomed & Biotechnol), 18(3):233-238.

[10]Smith CA, de Lacey S, Chapman M, et al., 2018. Effect of acupuncture vs sham acupuncture on live births among women undergoing in vitro fertilization: a randomized clinical trial. JAMA, 319(19):1990-1998.

[11]Vahratian A, Smith YR, Dorman M, et al., 2011. Longitudinal depressive symptoms and state anxiety among women using assisted reproductive technology. Fertil Steril, 95(3):1192-1194.

[12]Wang FF, Pan JX, Wu Y, et al., 2018a. American, European, and Chinese practice guidelines or consensuses of polycystic ovary syndrome: a comparative analysis. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 19(5):354-363.

[13]Wang FF, Wu Y, Zhu YH, et al., 2018b. Pharmacologic therapy to induce weight loss in women who have obesity/ overweight with polycystic ovary syndrome: a systematic review and network meta-analysis. Obes Rev, 19(10):1424-1445.

[14]Wu Y, Robinson N, Hardiman PJ, et al., 2016. Acupuncture for treating polycystic ovary syndrome: guidance for future randomized controlled trials. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 17(3):169-180.

[15]Xing LF, Wu Y, He YJ, et al., 2018. Transcutaneous electrical acupoint stimulation alleviates the anxiety levels of IVF: a prospective, randomized and controlled study. Eur J Integr Med, 20:126-130.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - Journal of Zhejiang University-SCIENCE