Full Text:   <337>

CLC number: 

On-line Access: 2021-10-14

Received: 2021-05-10

Revision Accepted: 2021-09-07

Crosschecked: 0000-00-00

Cited: 0

Clicked: 924

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
Open peer comments

Journal of Zhejiang University SCIENCE B 1998 Vol.-1 No.-1 P.

http://doi.org/10.1631/jzus.B2100420


Molecular hydrogen is a promising therapeutic agent for pulmonary disease


Author(s):  Zhiling FU, Jin ZHANG

Affiliation(s):  Department of Anesthesiology, Shengjing Hospital of China Medical University, Shenyang, 110004, China

Corresponding email(s):   zhangjin11170@163.com

Key Words:  Molecular hydrogen, Pulmonary diseases, Reactive oxygen species (ROS), Oxidative stress, Inflammation


Zhiling FU, Jin ZHANG. Molecular hydrogen is a promising therapeutic agent for pulmonary disease[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .

@article{title="Molecular hydrogen is a promising therapeutic agent for pulmonary disease",
author="Zhiling FU, Jin ZHANG",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2100420"
}

%0 Journal Article
%T Molecular hydrogen is a promising therapeutic agent for pulmonary disease
%A Zhiling FU
%A Jin ZHANG
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2100420

TY - JOUR
T1 - Molecular hydrogen is a promising therapeutic agent for pulmonary disease
A1 - Zhiling FU
A1 - Jin ZHANG
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2100420


Abstract: 
molecular hydrogen exerts biological effects on nearly all organs. It has anti-oxidative, anti-inflammatory, and anti-aging effects and contributes to the regulation of autophagy and cell death. As the primary organ for gas exchange, the lungs are constantly exposed to various harmful environmental irritants. Short- or long-term exposure to these harmful substances often results in lung injury, causing respiratory and lung diseases. Acute and chronic respiratory diseases have high rates of morbidity and mortality and have become a major public health concern worldwide. For example, coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 has become a global pandemic since it emerged in Wuhan, China. An increasing number of studies have revealed that hydrogen may protect the lungs from diverse diseases, including acute lung injury, chronic obstructive pulmonary disease, asthma, lung cancer, pulmonary arterial hypertension, and pulmonary fibrosis. In this review, we highlight the multiple functions of hydrogen and the mechanisms underlying its protective effects in various lung diseases, with a focus on its roles in disease pathogenesis and clinical significance.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - Journal of Zhejiang University-SCIENCE