Full Text:  <218>

Summary:  <55>

CLC number: 

On-line Access: 2024-02-01

Received: 2023-03-16

Revision Accepted: 2023-07-23

Crosschecked: 2024-02-02

Cited: 0

Clicked: 319

Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Wujiang SHI

https://orcid.org/0009-0009-2491-787X

Yi XU

https://orcid.org/0000-0003-2720-0005

Yunfu CUI

https://orcid.org/0000-0001-7393-1680

Xiangyu ZHONG

https://orcid.org/0009-0006-9581-741X

-   Go to

Article info.
Open peer comments

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)


Utilization of 3D printing technology in hepatopancreatobiliary surgery


Author(s):  Wujiang SHI, Jiangang WANG, Jianjun GAO, Xinlei ZOU, Qingfu DONG, Ziyue HUANG, Jialin SHENG, Canghai GUAN, Yi XU, Yunfu CUI, Xiangyu ZHONG

Affiliation(s):  Department of Hepatopancreatobiliary Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China; more

Corresponding email(s):  zhongxiangyu@hrbmu.edu.cn, yfui7@163.com, xuyihrb@pathology.hku.hk

Key Words:  3D printing; Hepatopancreatobiliary surgery; Organ model; Cancer model


Share this article to: More <<< Previous Paper|Next Paper >>>

Wujiang SHI, Jiangang WANG, Jianjun GAO, Xinlei ZOU, Qingfu DONG, Ziyue HUANG, Jialin SHENG, Canghai GUAN, Yi XU, Yunfu CUI, Xiangyu ZHONG. Utilization of 3D printing technology in hepatopancreatobiliary surgery[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2300175

@article{title="Utilization of 3D printing technology in hepatopancreatobiliary surgery",
author="Wujiang SHI, Jiangang WANG, Jianjun GAO, Xinlei ZOU, Qingfu DONG, Ziyue HUANG, Jialin SHENG, Canghai GUAN, Yi XU, Yunfu CUI, Xiangyu ZHONG",
journal="Journal of Zhejiang University Science B",
year="in press",
publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.B2300175"
}

%0 Journal Article
%T Utilization of 3D printing technology in hepatopancreatobiliary surgery
%A Wujiang SHI
%A Jiangang WANG
%A Jianjun GAO
%A Xinlei ZOU
%A Qingfu DONG
%A Ziyue HUANG
%A Jialin SHENG
%A Canghai GUAN
%A Yi XU
%A Yunfu CUI
%A Xiangyu ZHONG
%J Journal of Zhejiang University SCIENCE B
%P 123-134
%@ 1673-1581
%D in press
%I Zhejiang University Press & Springer
doi="https://doi.org/10.1631/jzus.B2300175"

TY - JOUR
T1 - Utilization of 3D printing technology in hepatopancreatobiliary surgery
A1 - Wujiang SHI
A1 - Jiangang WANG
A1 - Jianjun GAO
A1 - Xinlei ZOU
A1 - Qingfu DONG
A1 - Ziyue HUANG
A1 - Jialin SHENG
A1 - Canghai GUAN
A1 - Yi XU
A1 - Yunfu CUI
A1 - Xiangyu ZHONG
J0 - Journal of Zhejiang University Science B
SP - 123
EP - 134
%@ 1673-1581
Y1 - in press
PB - Zhejiang University Press & Springer
ER -
doi="https://doi.org/10.1631/jzus.B2300175"


Abstract: 
The technology of three-dimensional (3D) printing emerged in the late 1970s and has since undergone considerable development to find numerous applications in mechanical engineering, industrial design, and biomedicine. In biomedical science, several studies have initially found that 3D printing technology can play an important role in the treatment of diseases in hepatopancreatobiliary surgery. For example, 3D printing technology has been applied to create detailed anatomical models of disease organs for preoperative personalized surgical strategies, surgical simulation, intraoperative navigation, medical training, and patient education. Moreover, cancer models have been created using 3D printing technology for the research and selection of chemotherapy drugs. With the aim to clarify the development and application of 3D printing technology in hepatopancreatobiliary surgery, we introduce seven common types of 3D printing technology and review the status of research and application of 3D printing technology in the field of hepatopancreatobiliary surgery.

3D打印技术在肝胆胰外科中的应用进展

史武江1,王健岗2,高坚钧1,邹欣蕾1,董青福1,黄子越1,盛嘉麟1,关沧海1,徐艺1,3,4,5,6,7,8,9,崔云甫1,钟翔宇1
1哈尔滨医科大学附属第二医院肝胆胰外科,中国哈尔滨市,150086
2空军军医大学唐都医院普外科,中国西安市,710032
3遵义医科大学基础药理学教育部重点实验室,中国遵义市,563006
4厦门医学院临床转化医学重点实验室,中国厦门市,361000
5香港大学李嘉诚医学院病理科,中国香港特别行政区
6江苏省肿瘤靶向纳米诊断与治疗材料工程研究中心,中国盐城市,224007
7浙江省生物标志物与体外诊断转化重点实验室,中国杭州市,310053
8福建医科大学基础医学院胃肠道肿瘤教育部重点实验室,中国福州市,350122
9哈尔滨医科大学心肌缺血教育部重点实验室,中国哈尔滨市,150086
摘要:3D打印技术兴起于20世纪70年代末,经历长期的发展后,在机械工程、工业设计和生物医学领域得到了广泛的应用。在生物医学领域,多项研究初步发现3D打印技术可在肝胆胰外科相关疾病的治疗中发挥重要作用。例如,3D打印技术已被应用于创建疾病器官的详细解剖模型,用于术前制定个性化手术策略、手术模拟、术中导航、医师培训和患者教育。此外,还可利用3D打印技术创建癌症模型,用于化疗药物的研究和选择。为了阐明3D打印技术在肝胆胰外科领域的发展和应用现状,本文介绍了七种常见的3D打印技术,并对3D打印技术在肝胆胰外科领域的研究和应用现状进行了综述。

关键词组:3D打印;肝胆胰外科;器官模型;癌症模型

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]AgungNP, NadhifMH, IrdamGA, et al., 2021. The role of 3D-printed phantoms and devices for organ-specified appliances in urology. Int J Bioprint, 7(2):333.

[2]AllanA, KealleyC, SquelchA, et al., 2019. Patient-specific 3D printed model of biliary ducts with congenital cyst. Quant Imaging Med Surg, 9(1):86-93.

[3]AndolfiC, PlanaA, KaniaP, et al., 2017. Usefulness of three-dimensional modeling in surgical planning, resident training, and patient education. J Laparoendosc Adv Surg Tech A, 27(5):512-515.

[4]AseniP, SantanielloT, RizzettoF, et al., 2021. Hybrid additive fabrication of a transparent liver with biosimilar haptic response for preoperative planning. Diagnostics, 11(9):1734.

[5]AwadA, FinaF, GoyanesA, et al., 2020. 3D printing: prin

[6]ciples and pharmaceutical applications of selective laser sintering. Int J Pharm, 586:119594.

[7]AwadA, FinaF, GoyanesA, et al., 2021. Advances in powder bed fusion 3D printing in drug delivery and healthcare. Adv Drug Deliv Rev, 174:406-424.

[8]BallardDH, WakeN, WitowskiJ, et al., 2020. Radiological society of north america (RSNA) 3D printing special interest group (SIG) clinical situations for which 3D printing is considered an appropriate representation or extension of data contained in a medical imaging examination: abdominal, hepatobiliary, and gastrointestinal conditions. 3D Print Med, 6:13.

[9]BassousNJ, JonesCL, WebsterTJ, 2019. 3-D printed Ti-6Al-4V scaffolds for supporting osteoblast and restricting bacterial functions without using drugs: predictive equations and experiments. Acta Biomater, 96:662-673.

[10]BatiAH, GulerE, OzerMA, et al., 2020. Surgical planning with patient-specific three-dimensional printed pancreaticobiliary disease models-cross-sectional study. Int J Surg, 80:175-183.

[11]BoseS, BhattacharjeeA, BanerjeeD, et al., 2021. Influence of random and designed porosities on 3D printed tricalcium phosphate-bioactive glass scaffolds. Addit Manuf, 40:101895.

[12]BurdallOC, MakinE, DavenportM, et al., 2016. 3D printing to simulate laparoscopic choledochal surgery. J Pediatr Surg, 51(5):828-831.

[13]Casas-MurilloC, Zuñiga-RuizA, Lopez-BarronRE, et al., 2021. 3D-printed anatomical models of the cystic duct and its variants, a low-cost solution for an in-house built simulator for laparoscopic surgery training. Surg Radiol Anat, 43(4):537-544.

[14]ChedidVG, KamathAA, KnudsenMJ, et al., 2020. Three-dimensional-printed liver model helps learners identify hepatic subsegments: a randomized-controlled cross-over trial. Am J Gastroenterol, 115(11):1906-1910.

[15]ChenCY, TsouYF, YehYT, et al., 2022. Advanced preoperative three-dimensional planning decreases the surgical complications of using large-for-size grafts in pediatric living donor liver transplantation. J Pediatr Surg, 57(7):1210-1214.

[16]ChenH, HeYC, JiaWD, 2020. Precise hepatectomy in the intelligent digital era. Int J Biol Sci, 16(3):365-373.

[17]ChenJY, LiuXJ, TianYJ, et al., 2022. 3D-printed anisotropic polymer materials for functional applications. Adv Mater, 34(5):2102877.

[18]ChengJ, WangZF, LiuJ, et al., 2022. Value of 3D printing technology combined with indocyanine green fluorescent navigation in complex laparoscopic hepatectomy. PLoS ONE, 17(8):e0272815.

[19]da Conceicao RibeiroR, PalD, FerreiraAM, et al., 2019. Reactive jet impingement bioprinting of high cell density gels for bone microtissue fabrication. Biofabrication, 11(1):015014.

[20]DerbyB, 2012. Printing and prototyping of tissues and scaffolds. Science, 338(6109):921-926.

[21]FangCH, ZhangP, QiXL, 2019. Digital and intelligent liver surgery in the new era: prospects and dilemmas. eBioMedicine, 41:693-701.

[22]FonsecaAC, MelchelsFPW, FerreiraMJS, et al., 2020. Emulating human tissues and organs: a bioprinting perspective toward personalized medicine. Chem Rev, 120(19):11093-11139.

[23]GooHW, ParkSJ, YooSJ, 2020. Advanced medical use of three-dimensional imaging in congenital heart disease: augmented reality, mixed reality, virtual reality, and three-dimensional printing. Korean J Radiol, 21(2):133-145.

[24]GuillaumeO, GevenMA, SprecherCM, et al., 2017. Surface-enrichment with hydroxyapatite nanoparticles in stereolithography-fabricated composite polymer scaffolds promotes bone repair. Acta Biomater, 54:386-398.

[25]HanCJ, FangQH, ShiYS, et al., 2020. Recent advances on high-entropy alloys for 3D printing. Adv Mater, 32(26):1903855.

[26]HanT, YangXD, XuY, et al., 2017. Therapeutic value of 3-D printing template-assisted 125I-seed implantation in the treatment of malignant liver tumors. OncoTargets Ther, 10:3277-3283.

[27]HuangW, LuJ, ChenKM, et al., 2018. Preliminary application of 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with advanced pancreatic cancer. World J Gastroenterol, 24(46):5280-5287.

[28]HuberT, HuettlF, TripkeV, et al., 2021. Experiences with three-dimensional printing in complex liver surgery. Ann Surg, 273(1):e26-e27.

[29]HungBP, NavedBA, NybergEL, et al., 2016. Three-dimensional printing of bone extracellular matrix for craniofacial regeneration. ACS Biomater Sci Eng, 2(10):1806-1816.

[30]IgamiT, NakamuraY, HiroseT, et al., 2014. Application of a three-dimensional print of a liver in hepatectomy for small tumors invisible by intraoperative ultrasonography: preliminary experience. World J Surg, 38(12):3163-3166.

[31]IkegamiT, MaeharaY, 2013. Transplantation:3D printing of the liver in living donor liver transplantation. Nat Rev Gastroenterol Hepatol, 10(12):697-698.

[32]JinZBY, LiYR, YuK, et al., 2021. 3D printing of physical organ models: recent developments and challenges. Adv Sci, 8(17):2101394.

[33]JingX, FuHX, YuBJ, et al., 2022. Two-photon polymerization for 3D biomedical scaffolds: overview and updates. Front Bioeng Biotechnol, 10:994355.

[34]KimJH, HaDH, HanES, et al., 2022. Feasibility and safety of a novel 3D-printed biodegradable biliary stent in an in vivo porcine model: a preliminary study. Sci Rep, 12:15875.

[35]KongXX, NieLY, ZhangHJ, et al., 2016. Do three-dimensional visualization and three-dimensional printing improve hepatic segment anatomy teaching? A randomized controlled study. J Surg Educ, 73(2):264-269.

[36]LarondaMM, RutzAL, XiaoS, et al., 2017. A bioprosthetic ovary created using 3D printed microporous scaffolds restores ovarian function in sterilized mice. Nat Commun, 8:15261.

[37]LiSL, LiuSY, WangXH, 2022. Advances of 3D printing in vascularized organ construction. Int J Bioprint, 8(3):588.

[38]LiWL, MilleLS, RobledoJA, et al., 2020. Recent advances in formulating and processing biomaterial inks for vat polymerization-based 3D printing. Adv Healthc Mater, 9(15):2000156.

[39]LiangS, XieJ, WangFY, et al., 2021. Application of three-dimensional printing technology in peripheral hip diseases. Bioengineered, 12(1):5883-5891.

[40]LimHK, ChoiYJ, ChoiWC, et al., 2022. Reconstruction of maxillofacial bone defects using patient-specific long-lasting titanium implants. Sci Rep, 12:7538.

[41]LiuXX, YanJN, LiuJY, et al., 2021. Fabrication of a dual-layer cell-laden tubular scaffold for nerve regeneration and bile duct reconstruction. Biofabrication, 13(3):035038.

[42]Lopez-LopezV, Robles-CamposR, García-CalderonD, et al., 2021. Applicability of 3D-printed models in hepatobiliary surgey: results from “LIV3DPRINT” multicenter study. HPB, 23(5):675-684.

[43]MachekposhtiSA, MohavedS, NarayanRJ, 2019. Inkjet dispensing technologies: recent advances for novel drug discovery. Expert Opin Drug Discov, 14(2):101-113.

[44]MahmoudA, BennettM, 2015. Introducing 3-dimensional printing of a human anatomic pathology specimen: potential benefits for undergraduate and postgraduate education and anatomic pathology practice. Arch Pathol Lab Med, 139(8):1048-1051.

[45]MillerJS, StevensKR, YangMT, et al., 2012. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues. Nat Mater, 11(9):768-774.

[46]MüllerM, ÖztürkE, ArlovØ, et al., 2017. Alginate sulfate-nanocellulose bioinks for cartilage bioprinting applications. Ann Biomed Eng, 45(1):210-223.

[47]MusazziUM, KhalidGM, SelminF, et al., 2020. Trends in the production methods of orodispersible films. Int J Pharm, 576:118963.

[48]NgWL, LeeJM, ZhouMM, et al., 2020. Vat polymerization-based bioprinting-process, materials, applications and regulatory challenges. Biofabrication, 12(2):022001.

[49]ParkS, ChoiGS, KimJM, et al., 2022. 3D printing model of abdominal cavity of liver transplantation recipient to prevent large-for-size syndrome. Int J Bioprint, 8(4):609.

[50]PlaconeJK, EnglerAJ, 2018. Recent advances in extrusion-based 3D printing for biomedical applications. Adv Healthc Mater, 7(8):1701161.

[51]PuglieseL, MarconiS, NegrelloE, et al., 2018. The clinical use of 3D printing in surgery. Updates Surg, 70(3):‍381-388.

[52]RenzJF, BusuttilRW, 2000. Adult-to-adult living-donor liver transplantation: a critical analysis. Semin Liver Dis, 20(4):411-424.

[53]RhuJ, KimMS, KimS, et al., 2021. Application of three-dimensional printing for intraoperative guidance during liver resection of a hepatocellular carcinoma with sophisticated location. Ann Hepatobiliary Pancreat Surg, 25(2):265-269.

[54]RyuDJ, BanHY, JungEY, et al., 2020. Osteo-compatibility of 3D titanium porous coating applied by direct energy deposition (DED) for a cementless total knee arthroplasty implant: in vitro and in vivo study. J Clin Med, 9(2):478.

[55]SampognaG, PuglieseR, ElliM, et al., 2017. Routine clin

[56]ical application of virtual reality in abdominal surgery. Minim Invasive Ther Allied Technol, 26(3):135-143.

[57]SiegelRL, MillerKD, FuchsHE, et al., 2021. Cancer statistics, 2021. CA Cancer J Clin, 71(1):7-33.

[58]SongC, MinJH, JeongWK, et al., 2023. Use of individualized 3D-printed models of pancreatic cancer to improve surgeons’ anatomic understanding and surgical planning. Eur Radiol, 33:7646-7655.

[59]ten HoveA, de MeijerVE, HulscherJBF, et al., 2018. Meta-analysis of risk of developing malignancy in congenital choledochal malformation. Br J Surg, 105(5):482-490.

[60]Valls-EsteveA, Tejo-OteroA, Lustig-GainzaP, et al., 2023. Patient-specific 3D printed soft models for liver surgical planning and hands-on training. Gels, 9(4):339.

[61]VazVM, KumarL, 2021. 3D printing as a promising tool in personalized medicine. AAPS PharmSciTech, 22:49.

[62]WangJZ, XiongNY, ZhaoLZ, et al., 2018. Review fantastic medical implications of 3D-printing in liver surgeries, liver regeneration, liver transplantation and drug hepatotoxicity testing: a review. Int J Surg, 56:1-6.

[63]WangWJ, SunJ, 2021. Dimensional accuracy and clinical adaptation of ceramic crowns fabricated with the stereolithography technique. J Prosthet Dent, 125(4):657-663.

[64]WangYM, WuD, WuGH, et al., 2020. Metastasis-on-a-chip mimicking the progression of kidney cancer in the liver for predicting treatment efficacy. Theranostics, 10(1):‍300-311.

[65]WangYY, MullertzA, RantanenJ, 2022. Additive manufacturing of solid products for oral drug delivery using binder jetting three-dimensional printing. AAPS PharmSciTech, 23(6):196.

[66]WitowskiJ, PędziwiatrM, MajorP, et al., 2017. Cost-effective, personalized, 3D-printed liver model for preoperative planning before laparoscopic liver hemihepatectomy for colorectal cancer metastases. Int J Comput Assist Radiol Surg, 12(12):2047-2054.

[67]WitowskiJ, BudzyńskiA, GrochowskaA, et al., 2020. Decision-making based on 3D printed models in laparoscopic liver resections with intraoperative ultrasound: a prospective observational study. Eur Radiol, 30(3):1306-1312.

[68]XiangN, FangC, FanY, et al., 2015. Application of liver three-dimensional printing in hepatectomy for complex massive hepatocarcinoma with rare variations of portal vein: preliminary experience. Int J Clin Exp Med, 8(10):18873-18878.

[69]XieFH, SunLJ, PangY, et al., 2021. Three-dimensional bio-printing of primary human hepatocellular carcinoma for personalized medicine. Biomaterials, 265:120416.

[70]YangHY, SunLJ, PangY, et al., 2021. Three-dimensional bioprinted hepatorganoids prolong survival of mice with liver failure. Gut, 70(3):567-574.

[71]YangTY, TanTB, YangJL, et al., 2018. The impact of using three-dimensional printed liver models for patient education. J Int Med Res, 46(4):1570-1578.

[72]YangY, ZhouZY, LiuR, et al., 2018. Application of 3D visualization and 3D printing technology on ERCP for patients with hilar cholangiocarcinoma. Exp Ther Med, 15(4):3259-3264.

[73]ZeinNN, HanounehIA, BishopPD, et al., 2013. Three-dimensional print of a liver for preoperative planning in living donor liver transplantation. Liver Transpl, 19(12):1304-1310.

[74]ZengN, YangJ, XiangN, et al., 2020. Application of 3D visualization and 3D printing in individualized precision surgery for Bismuth-Corlette type III and IV hilar cholangiocarcinoma. J Southern Med Univ, 40(8):‍1172-1177 (in Chinese).

[75]ZhangAP, QuX, SomanP, et al., 2012. Rapid fabrication of complex 3D extracellular microenvironments by dynamic optical projection stereolithography. Adv Mater, 24(31):4266-4270.

[76]ZhangYY, XiaJF, ZhangJY, et al., 2022. Validity of a soft and flexible 3D-printed nissen fundoplication model in surgical training. Int J Bioprint, 8(2):546.

[77]ZhuW, MaXY, GouML, et al., 2016. 3D printing of functional biomaterials for tissue engineering. Curr Opin Biotechnol, 40:103-112.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE