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Multi-length scale bioprinting towards simulating microenvironmental cues
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Elisabeth L Gill, Xia Li, Mark A. Birch, Yan Yan Shery Huang. Multi-length scale bioprinting towards simulating microenvironmental cues[J]. Journal of Zhejiang University Science D, 2018, 1(2): 77-88.
@article{title="Multi-length scale bioprinting towards simulating microenvironmental cues",
author="Elisabeth L Gill, Xia Li, Mark A. Birch, Yan Yan Shery Huang",
journal="Journal of Zhejiang University Science D",
volume="1",
number="2",
pages="77-88",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-018-0014-1"
}
%0 Journal Article
%T Multi-length scale bioprinting towards simulating microenvironmental cues
%A Elisabeth L Gill
%A Xia Li
%A Mark A. Birch
%A Yan Yan Shery Huang
%J Journal of Zhejiang University SCIENCE D
%V 1
%N 2
%P 77-88
%@ 1869-1951
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-018-0014-1
TY - JOUR
T1 - Multi-length scale bioprinting towards simulating microenvironmental cues
A1 - Elisabeth L Gill
A1 - Xia Li
A1 - Mark A. Birch
A1 - Yan Yan Shery Huang
J0 - Journal of Zhejiang University Science D
VL - 1
IS - 2
SP - 77
EP - 88
%@ 1869-1951
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-018-0014-1
Abstract: It is envisaged that the creation of cellular environments at multiple length scales, that recapitulate in vivo bioactive and structural roles, may hold the key to creating functional, complex tissues in the laboratory. This review considers recent advances in biofabrication and bioprinting techniques across different length scales. Particular focus is placed on 3D printing of hydrogels and fabrication of biomaterial fibres that could extend the feature resolution and material functionality of soft tissue constructs. The outlook from this review discusses how one might create and simulate microenvironmental cues in vitro. A fabrication platform that integrates the competencies of different biofabrication technologies is proposed. Such a multi-process, multiscale fabrication strategy may ultimately translate engineering capability into an accessible life sciences toolkit, fulfilling its potential to deliver in vitro disease models and engineered tissue implants.
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