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Recent advances indesign andapplications ofbiomimetic self?assembled peptide hydrogels forhard tissue regeneration
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HaniyehNajaf, MahboobehJafari, GhazalFarahavar, SamiraSadatAbolmaali, NegarAzarpira, SedighehBorandeh, RahelehRavanfar. Recent advances indesign andapplications ofbiomimetic self?assembled peptide hydrogels forhard tissue regeneration[J]. Journal of Zhejiang University Science D, 2021, 4(4): 735-756.
@article{title="Recent advances indesign andapplications ofbiomimetic self?assembled peptide hydrogels forhard tissue regeneration",
author="HaniyehNajaf, MahboobehJafari, GhazalFarahavar, SamiraSadatAbolmaali, NegarAzarpira, SedighehBorandeh, RahelehRavanfar",
journal="Journal of Zhejiang University Science D",
volume="4",
number="4",
pages="735-756",
year="2021",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-021-00149-0"
}
%0 Journal Article
%T Recent advances indesign andapplications ofbiomimetic self?assembled peptide hydrogels forhard tissue regeneration
%A HaniyehNajaf
%A MahboobehJafari
%A GhazalFarahavar
%A SamiraSadatAbolmaali
%A NegarAzarpira
%A SedighehBorandeh
%A RahelehRavanfar
%J Journal of Zhejiang University SCIENCE D
%V 4
%N 4
%P 735-756
%@ 1869-1951
%D 2021
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-021-00149-0
TY - JOUR
T1 - Recent advances indesign andapplications ofbiomimetic self?assembled peptide hydrogels forhard tissue regeneration
A1 - HaniyehNajaf
A1 - MahboobehJafari
A1 - GhazalFarahavar
A1 - SamiraSadatAbolmaali
A1 - NegarAzarpira
A1 - SedighehBorandeh
A1 - RahelehRavanfar
J0 - Journal of Zhejiang University Science D
VL - 4
IS - 4
SP - 735
EP - 756
%@ 1869-1951
Y1 - 2021
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-021-00149-0
Abstract: The development of natural biomaterials applied for hard tissue repair and regeneration is of great importance, especially
in societies with a large elderly population. Self-assembled peptide hydrogels are a new generation of biomaterials that
provide excellent biocompatibility, tunable mechanical stability, injectability, trigger capability, lack of immunogenic reactions, and the ability to load cells and active pharmaceutical agents for tissue regeneration. Peptide-based hydrogels are
ideal templates for the deposition of hydroxyapatite crystals, which can mimic the extracellular matrix. Thus, peptide-based
hydrogels enhance hard tissue repair and regeneration compared to conventional methods. This review presents three major
self-assembled peptide hydrogels with potential application for bone and dental tissue regeneration, including ionic selfcomplementary peptides, amphiphilic (surfactant-like) peptides, and triple-helix (collagen-like) peptides. Special attention
is given to the main bioactive peptides, the role and importance of self-assembled peptide hydrogels, and a brief overview on
molecular simulation of self-assembled peptide hydrogels applied for bone and dental tissue engineering and regeneration.
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