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Suppl. Mater.: 

CLC number: R735.7

On-line Access: 2024-08-27

Received: 2023-10-17

Revision Accepted: 2024-05-08

Crosschecked: 2019-09-12

Cited: 0

Clicked: 4710

Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Hai-tao Yu

https://orcid.org/0000-0003-2342-5397

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Journal of Zhejiang University SCIENCE B 2019 Vol.20 No.11 P.928-932

http://doi.org/10.1631/jzus.B1900343


Integrated analysis of hypoxia-induced miR-210 signature as a potential prognostic biomarker of hepatocellular carcinoma: a study based on The Cancer Genome Atlas


Author(s):  Yi Dai, Ji-liang Shen, Xue-yong Zheng, Tian-yu Lin, Hai-tao Yu

Affiliation(s):  Zhejiang Provincial Key Laboratory of Laparoscopic Technology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China; more

Corresponding email(s):   3411053@zju.edu.cn

Key Words:  miR-210, The Cancer Genome Atlas (TCGA), Hepatocellular carcinoma (HCC), Hypoxia, prognostic biomarker



Abstract: 
hepatocellular carcinoma (HCC) is one of the most common types of liver cancer and is the second leading cause of cancer mortality with an estimated 745 500 deaths annually (Jemal et al., 2011). Although new therapeutic modalities including novel chemotherapeutic interventions and targeted therapy have been applied, the prognosis of HCC patients remains unsatisfactory due to the high incidence of intrahepatic and distal metastases (Siegel et al., 2018).

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