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Journal of Zhejiang University SCIENCE A 2002 Vol.3 No.2 P.243~246

http://doi.org/10.1631/jzus.2002.0243


Study of sEGF level in chronic atrophic gastritis with either Chinese traditional medicine or western medicine


Author(s):  SI Jian-min, SUN Lei-min, DAI Nin, QIAO Qiao, ZHOU Heng-de, ZHU Shu-dong

Affiliation(s):  Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China; more

Corresponding email(s): 

Key Words:  Epidermal growth factor (EGF), Chronic atrophic gastritis (CAG), Chinese traditional medicine


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SI Jian-min, SUN Lei-min, DAI Nin, QIAO Qiao, ZHOU Heng-de, ZHU Shu-dong. Study of sEGF level in chronic atrophic gastritis with either Chinese traditional medicine or western medicine[J]. Journal of Zhejiang University Science A, 2002, 3(2): 243~246.

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author="SI Jian-min, SUN Lei-min, DAI Nin, QIAO Qiao, ZHOU Heng-de, ZHU Shu-dong",
journal="Journal of Zhejiang University Science A",
volume="3",
number="2",
pages="243~246",
year="2002",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2002.0243"
}

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%A SI Jian-min
%A SUN Lei-min
%A DAI Nin
%A QIAO Qiao
%A ZHOU Heng-de
%A ZHU Shu-dong
%J Journal of Zhejiang University SCIENCE A
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%P 243~246
%@ 1869-1951
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2002.0243

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T1 - Study of sEGF level in chronic atrophic gastritis with either Chinese traditional medicine or western medicine
A1 - SI Jian-min
A1 - SUN Lei-min
A1 - DAI Nin
A1 - QIAO Qiao
A1 - ZHOU Heng-de
A1 - ZHU Shu-dong
J0 - Journal of Zhejiang University Science A
VL - 3
IS - 2
SP - 243
EP - 246
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2002.0243


Abstract: 
This study was aimed to investigate the level of sEGF in CAG with different therapies of either chinese traditional medicine or western medicine. Patients were divided into spleen-reinforcing I, spleen-reinforcing II, dampness-resolving and western medicine group by Differentiation Syndrome. Healthy volunteers acted as controls. The sEGF was investigated before and after treatment. The level of sEGF in CAG was higher than that in control group (P<0.01). In patients of spleen-reinforcing I group and spleen-reinforcing II group, the symptoms and pathological manifestations were improved dramatically (P<0.01) and sEGF dropped markedly after treatment (P<0.01 and P<0.05).The level of sEGF in the dampness-resolving group increased after treatment (P<0.05). But the level of sEGF in the western-medicine group dropped a little after treatment (P>0.05). The inflammation of gastric mucosa may cause the elevation of sEGF in CAG reflectively. After being effectively treated with chinese traditional medicine, the symptoms of CAG improved simultaneously with the return of sEGF. SEGF is a sensitive index to prognosis of CAG.

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