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Received: 2005-10-08

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Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.10 P.806-816


Computational prediction of microRNA genes in silkworm genome

Author(s):  TONG Chuan-zhou, JIN Yong-feng, ZHANG Yao-zhou

Affiliation(s):  Institute of Biochemistry, School of Life Science, Zhejiang University, Hangzhou 310029, China; more

Corresponding email(s):   jinyf@zju.edu.cn

Key Words:  miRNA, Silkworm, Computational prediction

TONG Chuan-zhou, JIN Yong-feng, ZHANG Yao-zhou. Computational prediction of microRNA genes in silkworm genome[J]. Journal of Zhejiang University Science B, 2006, 7(10): 806-816.

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journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T Computational prediction of microRNA genes in silkworm genome
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%A ZHANG Yao-zhou
%J Journal of Zhejiang University SCIENCE B
%V 7
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0806

T1 - Computational prediction of microRNA genes in silkworm genome
A1 - TONG Chuan-zhou
A1 - JIN Yong-feng
A1 - ZHANG Yao-zhou
J0 - Journal of Zhejiang University Science B
VL - 7
IS - 10
SP - 806
EP - 816
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2006.B0806

MicroRNAs (miRNAs) constitute a novel, extensive class of small RNAs (~21 nucleotides), and play important gene-regulation roles during growth and development in various organisms. Here we conducted a homology search to identify homologs of previously validated miRNAs from silkworm genome. We identified 24 potential miRNA genes, and gave each of them a name according to the common criteria. Interestingly, we found that a great number of newly identified miRNAs were conserved in silkworm and Drosophila, and family alignment revealed that miRNA families might possess single nucleotide polymorphisms. miRNA gene clusters and possible functions of complement miRNA pairs are discussed.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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