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Journal of Zhejiang University SCIENCE A 2007 Vol.8 No.7 P.999~1003

http://doi.org/10.1631/jzus.2007.A0999


Sm/TiCl4 (cat.) system-mediated intermolecular and intramolecular reductive coupling reactions of ketones with esters


Author(s):  LIU Yun-kui, XU Dan-qian, XU Zhen-yuan, ZHANG Yong-min

Affiliation(s):  State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Zhejiang University of Technology, Hangzhou 310014, China; more

Corresponding email(s):   ykuiliu@zjut.edu.cn, chrc@zjut.edu.cn

Key Words:  Samarium (Sm), Titanium tetrachloride (TiCl4), Ketone, Ester, Reductive coupling reaction


LIU Yun-kui, XU Dan-qian, XU Zhen-yuan, ZHANG Yong-min. Sm/TiCl4 (cat.) system-mediated intermolecular and intramolecular reductive coupling reactions of ketones with esters[J]. Journal of Zhejiang University Science A, 2007, 8(7): 999~1003.

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author="LIU Yun-kui, XU Dan-qian, XU Zhen-yuan, ZHANG Yong-min",
journal="Journal of Zhejiang University Science A",
volume="8",
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pages="999~1003",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.A0999"
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%T Sm/TiCl4 (cat.) system-mediated intermolecular and intramolecular reductive coupling reactions of ketones with esters
%A LIU Yun-kui
%A XU Dan-qian
%A XU Zhen-yuan
%A ZHANG Yong-min
%J Journal of Zhejiang University SCIENCE A
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%DOI 10.1631/jzus.2007.A0999

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T1 - Sm/TiCl4 (cat.) system-mediated intermolecular and intramolecular reductive coupling reactions of ketones with esters
A1 - LIU Yun-kui
A1 - XU Dan-qian
A1 - XU Zhen-yuan
A1 - ZHANG Yong-min
J0 - Journal of Zhejiang University Science A
VL - 8
IS - 7
SP - 999
EP - 1003
%@ 1673-565X
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.A0999


Abstract: 
Sm/TiCl4 system could well integrate the high reactivity of samarium(II) and high deoxygenation capacity of low valent titanium within one system. In this paper, the intermolecular and intramolecular reductive coupling reactions of ketones with esters mediated by metallic samarium (Sm) and a catalytic amount of titanium tetrachloride (TiCl4) were successfully developed. A series of substituted ketones and cyclic β-keto-esters were prepared in moderate to good yields under reflux and neutral conditions.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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