Full Text:   <807>

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CLC number: S852.2

On-line Access: 2018-05-05

Received: 2017-01-26

Revision Accepted: 2017-05-09

Crosschecked: 2018-04-19

Cited: 0

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Citations:  Bibtex RefMan EndNote GB/T7714


Xing-ting Liu


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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.5 P.390-399


Age-related changes of yolk precursor formation in the liver of laying hens

Author(s):  Xing-ting Liu, Xin Lin, Yu-ling Mi, Wei-dong Zeng, Cai-qiao Zhang

Affiliation(s):  Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China

Corresponding email(s):   cqzhang@zju.edu.cn

Key Words:  Lipid metabolism, Yolk precursor formation, 17β, -Estradiol, Antioxidant, Hen

Xing-ting Liu, Xin Lin, Yu-ling Mi, Wei-dong Zeng, Cai-qiao Zhang. Age-related changes of yolk precursor formation in the liver of laying hens[J]. Journal of Zhejiang University Science B, 2018, 19(5): 390-399.

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%T Age-related changes of yolk precursor formation in the liver of laying hens
%A Xing-ting Liu
%A Xin Lin
%A Yu-ling Mi
%A Wei-dong Zeng
%A Cai-qiao Zhang
%J Journal of Zhejiang University SCIENCE B
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%@ 1673-1581
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1700054

T1 - Age-related changes of yolk precursor formation in the liver of laying hens
A1 - Xing-ting Liu
A1 - Xin Lin
A1 - Yu-ling Mi
A1 - Wei-dong Zeng
A1 - Cai-qiao Zhang
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 5
SP - 390
EP - 399
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1700054

A rapid decline in egg production of laying hens begins after 480 d of age. Such a rapid decrease results predominantly from the ovarian aging, accompanied by endocrine changes, decreased yolk synthesis and accumulation, and the reduction in follicles selected into the preovulatory hierarchy. In this study, hens at 90, 150, 280, and 580 d old (D90, D150, D280, and D580, respectively) were compared for yolk precursor formation in the liver to elucidate effects of aging on laying performance. The results showed that liver lipid synthesis increased remarkably in hens from D90 to D150, but decreased sharply at D580 as indicated by the changes in triglyceride (TG) levels. This result was consistent with the age-related changes of the laying performance. The levels of liver antioxidants and total antioxidant capacity decreased significantly in D580 hens and the methane dicarboxylic aldehyde in D580 hens was much higher than that at other stages. The serum 17β;-Estradiol level increased from D90 to D280, but decreased at D580 (P<0.05). The expression of estrogen receptor α and β mRNAs in the liver displayed similar changes to the serum 17β;-Estradiol in D580 hens. Expressions of the genes related to yolk precursor formation and enzymes responsible for fat acid synthesis were all decreased in D580 hens. These results indicated that decreased yolk precursor formation in the liver of the aged hens resulted from concomitant decreases of serum 17β;-Estradiol level, transcription levels of estrogen receptors and critical genes involved in yolk precursor synthesis, and liver antioxidant status.




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