Full Text:   <469>

Summary:  <156>

CLC number: R735.7

On-line Access: 2018-11-02

Received: 2017-10-22

Revision Accepted: 2018-02-26

Crosschecked: 2018-10-22

Cited: 0

Clicked: 2676

Citations:  Bibtex RefMan EndNote GB/T7714


Yi-bin Xiao


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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.11 P.829-843


Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: a systematic review and meta-analysis

Author(s):  Yi-bin Xiao, Bo Zhang, Yu-lian Wu

Affiliation(s):  Department of Surgery, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

Corresponding email(s):   med_xyb@126.com, yulianwu@zju.edu.cn

Key Words:  Breast cancer liver metastasis, Radiofrequency ablation, Hepatic resection, Prognosis, Meta-analysis

Yi-bin Xiao, Bo Zhang, Yu-lian Wu. Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: a systematic review and meta-analysis[J]. Journal of Zhejiang University Science B, 2018, 19(11): 829-843.

@article{title="Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: a systematic review and meta-analysis",
author="Yi-bin Xiao, Bo Zhang, Yu-lian Wu",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: a systematic review and meta-analysis
%A Yi-bin Xiao
%A Bo Zhang
%A Yu-lian Wu
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 11
%P 829-843
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1700516

T1 - Radiofrequency ablation versus hepatic resection for breast cancer liver metastasis: a systematic review and meta-analysis
A1 - Yi-bin Xiao
A1 - Bo Zhang
A1 - Yu-lian Wu
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 11
SP - 829
EP - 843
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1700516

Objective: To evaluate the comparative therapeutic efficacy of radiofrequency ablation (RFA) and hepatic resection (HR) for breast cancer liver metastases (BCLMs). Methods: Studies that had examined the outcomes for both RFA and HR for BCLM were identified by searching the electronic databases PubMed, EMBASE, and the Cochrane Library. Pooled analyzes of the overall survival (OS), disease-free survival (DFS), and short-term outcomes of BCLM were performed. Results: Patients with BCLM gained many more survival benefits from HR than from RFA with regard to the 3-year OS rate (combined odds ratio (OR) 0.41, 95% confidence interval (CI) 0.29–0.59, P<0.001), 5-year OS rate (combined OR 0.38, 95% CI 0.32–0.46, P<0.001), 3-year DFS (combined OR 0.36, 95% CI 0.27–0.49, P<0.001), and 5-year DFS (combined OR 0.51, 95% CI 0.40–0.66, P<0.001). RFA had fewer postoperative complications (combined OR 0.30, 95% CI 0.20–0.44, P<0.001) and shorter hospital stays (combined OR −9.01, 95% CI −13.49–4.54, P<0.001) than HR. Conclusions: HR takes precedence over RFA in the treatment of patients with BCLM, considering the better survival rate. RFA gives rise to fewer complications and can be carried out with a shorter hospital stay, compared to HR. RFA should be reserved for patients who are not optimum candidates for resection.

Retraction of this paper was initiated at the authors' request, as they need to check the original data and analysis for the mistakes pointed out by independent researchers after the publication.


结论:HR比RFA对于提高BCLM患者生存率有更大 优势;RFA并发症少、可重复、患者术后住院时间短,具有明显微创优势.对于不适合行切除治疗的患者可考虑行RFA治疗.


Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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