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On-line Access: 2022-06-16

Received: 2022-03-28

Revision Accepted: 2022-05-19

Crosschecked: 2022-09-16

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Citations:  Bibtex RefMan EndNote GB/T7714




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Journal of Zhejiang University SCIENCE B 2022 Vol.23 No.9 P.770-777


Development and application of bionic systems consisting of tumor-cell membranes

Author(s):  Tianjiao PENG, Jun YAO

Affiliation(s):  Clinical Medical College, Henan University of Science and Technology, Luoyang 471003, China; more

Corresponding email(s):   yaojun74@163.com

Key Words:  Tumor cell membrane;Nanomedicine;Biomimetic nanoparticle, Drug delivery, Targeted therapy

Tianjiao PENG, Jun YAO. Development and application of bionic systems consisting of tumor-cell membranes[J]. Journal of Zhejiang University Science B, 2022, 23(9): 770-777.

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author="Tianjiao PENG, Jun YAO",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Development and application of bionic systems consisting of tumor-cell membranes
%A Tianjiao PENG
%A Jun YAO
%J Journal of Zhejiang University SCIENCE B
%V 23
%N 9
%P 770-777
%@ 1673-1581
%D 2022
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2200156

T1 - Development and application of bionic systems consisting of tumor-cell membranes
A1 - Tianjiao PENG
A1 - Jun YAO
J0 - Journal of Zhejiang University Science B
VL - 23
IS - 9
SP - 770
EP - 777
%@ 1673-1581
Y1 - 2022
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2200156

Malignant tumors pose a serious threat to human health but during the past decade, great progress has been made in the treatment of tumors. The tumor-cell membrane is well constructed and can be used to solve problems in tumor therapy. Tumor-cell membranes exhibit not only high biocompatibility due to their homology but also enhanced therapeutic effects when combined with nanotechnology. Meanwhile, nanomaterials show high selectivity, sensitivity, and clinical transformation potential. Enhanced immunotherapy or tumor vaccines have potential clinical application because of tumor-membrane surface-specific antigens. Several studies have confirmed the feasibility and advantages of using tumor-cell membrane-incorporated nanosystems for tumor therapy. Considering all this, we focus in this review on the application of tumor-cell-membrane bionic platforms and, in the summary, provide ideas for new scientific developments.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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