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 ORCID:

Marcin CHOLEWIŃSKI

https://orcid.org/0000-0003-3323-6143

Szymon CHOWAŃSKI

https://orcid.org/0000-0002-5667-1781

Jan LUBAWY

https://orcid.org/0000-0003-4030-3471

Arkadiusz URBAŃSKI

https://orcid.org/0000-0003-4875-4541

Karolina WALKOWIAK-NOWICKA

https://orcid.org/0000-0002-2490-3576

Paweł MARCINIAK

https://orcid.org/0000-0002-4790-001X

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Journal of Zhejiang University SCIENCE B 2024 Vol.25 No.5 P.389-409

http://doi.org/10.1631/jzus.B2300355


Short neuropeptide F in integrated insect physiology


Author(s):  Marcin CHOLEWIŃSKI, Szymon CHOWAŃSKI, Jan LUBAWY, Arkadiusz URBAŃSKI, Karolina WALKOWIAK-NOWICKA, Paweł MARCINIAK

Affiliation(s):  Department of Animal Physiology and Developmental Biology, Adam Mickiewicz University, Poznań 61-614, Poland

Corresponding email(s):   pmarcin@amu.edu.pl

Key Words:  Insect neuropeptide, Invertebrate neurobiology, Short neuropeptide F (sNPF), Feeding, Neurohormone


Marcin CHOLEWIŃSKI, Szymon CHOWAŃSKI, Jan LUBAWY, Arkadiusz URBAŃSKI, Karolina WALKOWIAK-NOWICKA, Paweł MARCINIAK. Short neuropeptide F in integrated insect physiology[J]. Journal of Zhejiang University Science B, 2024, 25(5): 389-409.

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journal="Journal of Zhejiang University Science B",
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year="2024",
publisher="Zhejiang University Press & Springer",
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A1 - Karolina WALKOWIAK-NOWICKA
A1 - Paweł MARCINIAK
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Abstract: 
The short neuropeptide F (sNPF) family of peptides is a multifunctional group of neurohormones involved in the regulation of various physiological processes in insects. They have been found in a broad spectrum of species, but the number of isoforms in the precursor molecule varies from one to four. The receptor for sNPF (sNPFR), which belongs to the G protein-coupled receptor family, has been characterized in various insect orders and was shown to be an ortholog of the mammalian prolactin-releasing peptide receptor (PrPR). The sNPF signaling pathway interacts with other neurohormones such as insulin-like peptides, SIFamide, and pigment-dispersing factors (PDFs) to regulate various processes. The main physiological function of sNPF seems to be involved in the regulation of feeding, but the observed effects are species-specific. sNPF is also connected with the regulation of foraging behavior and the olfactory system. The influence of sNPF on feeding and thus energy metabolism may also indirectly affect other vital processes, such as reproduction and development. In addition, these neurohormones are involved in the regulation of locomotor activity and circadian rhythm in insects. This review summarizes the current state of knowledge about the sNPF system in insects.

昆虫生理中短神经肽F的功能研究进展

Marcin CHOLEWI?SKI, Szymon CHOWA?SKI, Jan LUBAWY, Arkadiusz URBA?SKI, Karolina WALKOWIAK-NOWICKA, Pawe? MARCINIAK
亚当密茨凯维奇大学生物学院动物生理学和发育生物学系,波兰波兹南,61-614
摘要:短神经肽F(sNPF)肽家族是参与调控昆虫体内各种生理过程的多功能神经激素。它们广泛分布于生物体中,但前体分子中的异构体数量因物种而异,从一个到四个不等。sNPF受体(sNPFR)属于G蛋白偶联受体家族,在多种昆虫目中已有表征,并被证明是哺乳动物泌乳素释放肽受体(PrPR)的同源物。sNPF信号通路通过与其他神经激素(例如类胰岛素肽、SIFamide和色素分散因子(PDFs))的相互作用以调控多种生理过程。其主要生理功能涉及摄食的调节,但观察到的效应因物种而异。sNPF还与觅食行为和嗅觉系统的调节相关。其对摄食及能量代谢的影响还可能间接影响其他重要过程,例如繁殖和发育。此外,这些神经激素还参与昆虫的运动活动和昼夜节律的调节。本文回顾并总结了昆虫中sNPF系统的现阶段研究进展。

关键词:昆虫神经肽;无脊椎动物神经生物学;短神经肽F(sNPF);摄食;神经激素

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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