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Journal of Zhejiang University SCIENCE B 2013 Vol.14 No.8 P.705-712

http://doi.org/10.1631/jzus.BQICC704


Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion


Author(s):  Zhen Sun, Ying Shen, Lin Lu, Rui-yan Zhang, Li-jin Pu, Qi Zhang, Zheng-kun Yang, Jian Hu, Qiu-jing Chen, Wei-feng Shen

Affiliation(s):  Department of Cardiology, Shanghai Ruijin Hospital, Shanghai 200025, China; more

Corresponding email(s):   rjshenweifeng@gmail.com

Key Words:  Stable angina, Coronary collateral circulation, Risk factors, Angiography, Chronic total coronary occlusion


Zhen Sun, Ying Shen, Lin Lu, Rui-yan Zhang, Li-jin Pu, Qi Zhang, Zheng-kun Yang, Jian Hu, Qiu-jing Chen, Wei-feng Shen. Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion[J]. Journal of Zhejiang University Science B, 2013, 14(8): 705-712.

@article{title="Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion",
author="Zhen Sun, Ying Shen, Lin Lu, Rui-yan Zhang, Li-jin Pu, Qi Zhang, Zheng-kun Yang, Jian Hu, Qiu-jing Chen, Wei-feng Shen",
journal="Journal of Zhejiang University Science B",
volume="14",
number="8",
pages="705-712",
year="2013",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.BQICC704"
}

%0 Journal Article
%T Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion
%A Zhen Sun
%A Ying Shen
%A Lin Lu
%A Rui-yan Zhang
%A Li-jin Pu
%A Qi Zhang
%A Zheng-kun Yang
%A Jian Hu
%A Qiu-jing Chen
%A Wei-feng Shen
%J Journal of Zhejiang University SCIENCE B
%V 14
%N 8
%P 705-712
%@ 1673-1581
%D 2013
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.BQICC704

TY - JOUR
T1 - Clinical and angiographic features associated with coronary collateralization in stable angina patients with chronic total occlusion
A1 - Zhen Sun
A1 - Ying Shen
A1 - Lin Lu
A1 - Rui-yan Zhang
A1 - Li-jin Pu
A1 - Qi Zhang
A1 - Zheng-kun Yang
A1 - Jian Hu
A1 - Qiu-jing Chen
A1 - Wei-feng Shen
J0 - Journal of Zhejiang University Science B
VL - 14
IS - 8
SP - 705
EP - 712
%@ 1673-1581
Y1 - 2013
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.BQICC704


Abstract: 
Objective: coronary collateral circulation is an alternative source of blood supply to myocardium in the presence of advanced coronary artery disease. We sought to determine which clinical and angiographic variables are associated with collateral development in patients with stable angina and chronic total coronary occlusion. Methods: Demographic variables, biochemical measurements, and angiographic findings were collected from 478 patients with stable angina and chronic total coronary occlusion. The presence and extent of collaterals supplying the distal aspect of a total coronary occlusion from the contra-lateral vessel were graded from 0 to 3 according to the Rentrop scoring system. Results: Low (Rentrop score of 0 or 1) and high (Rentrop score of 2 or 3) coronary collateralizations were detected in 186 and 292 patients, respectively. Despite similar age, cigarette smoking, and medical treatment, patients with low collateralization were female in a higher proportion and less hypertensive, and had higher rates of type 2 diabetes and dyslipidemia than those with high collateralization (for all comparisons, P<0.05). In addition, patients with low collateralization exhibited more single-vessel disease, less right coronary artery occlusion, more impaired renal function, and higher serum levels of high-sensitivity C-reactive protein (hsCRP) compared with those with high collateralization. Multivariate analysis revealed that age of ≥65 years, female gender, diabetes, no history of hypertension, dyslipidemia, moderate to severe renal dysfunction, single-vessel disease, and elevated hsCRP levels were independently associated with low coronary collateralization. Conclusions: Coronary collateralization was reduced in almost 40% of stable angina patients with chronic total occlusion, which was related to clinical and angiographic factors. The impact of coronary collateralization on outcomes after revascularization needs further investigation.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]Boodhwani, M., Nakai, Y., Mieno, S., Voisine, P., Bianchi, C., Araujo, E.G., Feng, J., Michael, K., Li, J., Sellke, F.W., 2006. Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress. Ann. Thorac. Surg., 81(2):634-641.

[2]Choi, J.H., Chang, S.A., Choi, J.O., Song, Y.B., Hahn, J.Y., Choi, S.H., Lee, S.C., Lee, S.H., Oh, J.K., Choe, Y., et al., 2013. Frequency of myocardial infarction and its relationship to angiographic collateral flow in territories supplied by chronically occluded coronary arteries. Circulation, 127(6):703-709.

[3]Duran, M., Uysal, O.K., Gunebakmaz, O., Yilmaz, Y., Vatankulu, M.A., Turfan, M., Duran, A.O., Ornek, E., Cetim, M., Kaya, M.G., 2013. Renal impairment and coronary collaterals in patients with acute coronary syndrome. Herz, Epub ahead of print.

[4]Elsman, P., van(t Hof, A.W., de Boer, M.J., Hoorntje, J.C., Suryapranata, H., Dambrink, J.H., Zijlstra, F., 2004. Zwolle Myocardial Infarction Study Group. Role of collateral circulation in the acute phase of ST-segment elevation myocardial infarction treated with primary coronary intervention. Eur. Heart J., 25(10):854-858.

[5]Fefer, P., Knudtson, M.L., Cheema, A.N., Galbraith, P.D., Osherov, A.B., Yalonetsky, S., Gannot, S., Samuel, M., Weisbrod, M., Bierstone, D., et al., 2012. Current perspectives on coronary chronic total occlusions: the Canadian Multicenter Chronic Total Occlusions Registry. J. Am. Coll. Cardiol., 59(11):991-997.

[6]Fraker, T.D.Jr., Fihn, S.D., Gibbons, R.J., Abrams, J., Chatterjee, K., Daley, J., Deedwania, P.C., Douglas, J.S., Ferguson, T.B.Jr., Gardin, J.M., et al., 2007. Chronic angina focused update of the ACC/AHA 2002 guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 guidelines for the management of patients with chronic stable angina. J. Am. Coll. Cardiol., 50(23):2264-2274.

[7]Guray, U., Erbay, A.R., Guray, Y., Yilmaz, M.B., Boyaci, A.A., Sasmaz, H., Korkmaz, S., Kutuk, E., 2004. Poor coronary collateral circulation is associated with higher concentrations of soluble adhesion molecules in patients with single-vessel disease. Coron. Artery Dis., 15(7):413-417.

[8]Hsu, P.C., Juo, S.H., Su, H.M., Chen, S.C., Tsai, W.C., Lai, W.T., Sheu, S.H., Lin, T.H., 2012. Predictor of poor coronary collaterals in chronic kidney disease population with significant coronary artery disease. BMC Nephrol., 13(1):98-104.

[9]Imhof, B.A., Aurrand-Lions, M., 2006. Angiogenesis and inflammation face off. Nat. Med., 12(2):171-172.

[10]Kadi, H., Ceyhan, K., Karayakali, M., Celik, A., Ozturk, A., Koc, F., Onalan, O., 2011. Effects of prediabetes on coronary collateral circulation in patients with coronary artery disease. Coron. Artery Dis., 22(4):233-237.

[11]Kerner, A., Gruberg, L., Goldberg, A., Roguin, A., Lavie, P., Lavie, L., Markiewicz, W., Beyar, R., Aronson, D., 2007. Relation of C-reactive protein to coronary collaterals in patients with stable angina pectoris and coronary artery disease. Am. J. Cardiol., 99(4):509-512.

[12]Kersten, J.R., Toller, W.G., Tessmer, J.P., Pagel, P.S., Warltier, D.C., 2001. Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism. Am. J. Physiol. Heart Circ. Physiol., 281(5):H2097-H2104.

[13]Kilian, J.G., Keech, A., Adams, M.R., Celermajer, D.S., 2002. Coronary collateralization: determinants of adequate distal vessel filling after arterial occlusion. Coron. Artery Dis., 13(3):155-159.

[14]Levin, D.C., 1974. Pathways and functional significance of the coronary collateral circulation. Circulation, 50(4):831-837.

[15]Lin, T.H., Wang, C.L., Su, H.M., Hsu, P.C., Juo, S.H., Voon, W.C., Shin, S.J., Lai, W.T., Sheu, S.H., 2010. Functional vascular endothelial growth factor gene polymorphisms and diabetes: effect on coronary collaterals in patients with significant coronary artery disease. Clin. Chim. Acta, 411(21-22):1688-1693.

[16]Meier, P., 2011. The sword of Damocles: an illustrative example of the life-saving effect of the collateral circulation. J. Invasive Cardiol., 23(3):E47-E48.

[17]Meier, P., Hemingway, H., Lansky, A.J., Knapp, G., Pitt, B., Seiler, C., 2012. The impact of the coronary collateral circulation on mortality: a meta-analysis. Eur. Heart J., 33(5):614-621.

[18]Pu, L.J., Shen, Y., Zhang, R.Y., Zhang, Q., Ding, F.H., Hu, J., Yang, Z.K., Shen, W.F., 2012. Screening for significant atherosclerotic renal artery stenosis with a regression model in patients undergoing transradial coronary angiography/intervention. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 13(8):631-637.

[19]Regieli, J.J., Jukema, J.W., Nathore, H.M., Zwinderman, A.H., Ng, S., Grobbee, D.E., van der Graaf, Y., Doevendans, P.A., 2009. Coronary collaterals improve prognosis in patients with ischemic heart disease. Int. J. Cardiol., 132(2):257-262.

[20]Rentrop, K.P., Cohen, M., Blanke, H., Phillips, R.A., 1985. Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects. J. Am. Coll. Cardiol., 5(3):587-592.

[21]Rocic, P., 2012. Why is coronary collateral growth impaired in type II diabetes and the metabolic syndrome? Vascul. Pharmacol., 57(5-6):179-186.

[22]Schirmer, S.H., van Royen, N., Moerlan, P.D., Fledderus, J.O., Henriques, J.P., van der Schaaf, R.J., Vis, M.M., Baan, J.Jr., Koch, K.T., Horrevoets, A.J., et al., 2009. Local cytokine concentration and oxygen pressure are related to maturation of collateral circulation in humans. J. Am. Coll. Cardiol., 53(23):2141-2147.

[23]Seiler, C., 2010. The human coronary collateral circulation. Eur. J. Clin. Invest., 40(5):465-476.

[24]Shen, Y., Pu, L.J., Lu, L., Zhang, Q., Zhang, R.Y., Shen, W.F., 2012. Serum advanced glycation end-products and receptors as prognostic biomarkers in diabetics undergoing coronary artery stent implantation. Can. J. Cardiol., 28(6):737-743.

[25]Traupe, T., Gloekler, S., de Marchi, S.F., Werner, G.S., Seiler, C., 2010. Assessment of the human coronary collateral circulation. Circulation, 122(12):1210-1220.

[26]van der Hoeven, N.W., Teunissen, P.F., Werner, G.S., Delewi, R., Schirmer, S.H., Traupe, T., van der Laan, A.M., Tijssen, J.G., Piek, J.J., Seiler, C., et al., 2013. Clinical parameters associated with collateral development in patients with chronic total coronary occlusion. Heart, 99(15):1100-1105.

[27]Wang, S., Jing, J., Liu, C.F., Jiang, T.M., Yang, X.B., Zhou, Y., Chen, Y.D., 2013. The relationship between diastolic pressure and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion. Am. J. Hypertens., 26(5):630-635.

[28]Williamson, J.R., Ostrow, E., Eades, D., Chang, K., Allison, W., Kilo, C., Sherman, W.R., 1990. Glucose-induced microvascular functional changes in non-diabetic rats are stereospecific and are prevented by an aldose reductase inhibitor. J. Clin. Invest., 85(4):1167-1172.

[29]Xie, S.L., Li, H.Y., Deng, B.Q., Luo, N.S., Geng, D.F., Wang, J.F., Nie, R.Q., 2011. Poor coronary collateral vessel development in patients with mild to moderate renal insufficiency. Clin. Res. Cardiol., 100(3):227-233.

[30]Zorkun, C., Akkaya, E., Zoulu, A., Tandogan, I., 2013. Determinants of coronary collateral circulation in patients with coronary artery disease. Anadolu Kardiyol. Derg., 13:146-151.

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