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CLC number: TP399; R318

On-line Access: 2012-06-05

Received: 2011-11-08

Revision Accepted: 2012-02-02

Crosschecked: 2012-05-04

Cited: 6

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Journal of Zhejiang University SCIENCE C 2012 Vol.13 No.6 P.452-459


A submatrix-based P300 brain-computer interface stimulus presentation paradigm

Author(s):  Jin-he Shi, Ji-zhong Shen, Yu Ji, Feng-lei Du

Affiliation(s):  Department of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China; more

Corresponding email(s):   03dzxxsjh@zju.edu.cn, jzshen@zju.edu.cn

Key Words:  Brain-computer interface, Event-related potentials, P300 speller, Submatrix-based paradigm

Jin-he Shi, Ji-zhong Shen, Yu Ji, Feng-lei Du. A submatrix-based P300 brain-computer interface stimulus presentation paradigm[J]. Journal of Zhejiang University Science C, 2012, 13(6): 452-459.

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journal="Journal of Zhejiang University Science C",
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%A Ji-zhong Shen
%A Yu Ji
%A Feng-lei Du
%J Journal of Zhejiang University SCIENCE C
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.C1100328

T1 - A submatrix-based P300 brain-computer interface stimulus presentation paradigm
A1 - Jin-he Shi
A1 - Ji-zhong Shen
A1 - Yu Ji
A1 - Feng-lei Du
J0 - Journal of Zhejiang University Science C
VL - 13
IS - 6
SP - 452
EP - 459
%@ 1869-1951
Y1 - 2012
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.C1100328

The P300 event-related potential (ERP), with advantages of high stability and no need for initial training, is one of the most commonly used responses in brain-computer interface (BCI) applications. The row/column paradigm (RCP) that flashes an entire column or row of a visual matrix has been used successfully to help patients to spell words. However, RCP remains subject to errors that slow down communication, such as adjacency-distraction and double-flash errors. In this paper, a new visual stimulus presentation paradigm called the submatrix-based paradigm (SBP) is proposed. SBP divides a 6×6 matrix into several submatrices. Each submatrix flashes in single cell paradigm (SCP) mode and separately performs an ensemble averaging method according to the sequences. The parameter of sequence number is used to improve further the accuracy and information transfer rate (ITR). SBP has advantages of flexibility in division of the matrix and better expansion capability, which were confirmed with different divisions of the 6×6 matrix and expansion to a 6×9 matrix. Stimulation results show that SBP is superior to RCP in performance and user acceptability.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1]Chen, W.D., Zhang, J.H., Zhang, J.C., Li, Y., Qi, Y., Su, Y., Wu, B.A., Zhang, S.M., Dai, J.H., Zheng, X.X., et al., 2010. A P300 based online brain-computer interface system for virtual hand control. J. Zhejiang Univ.-Sci. C (Comput. & Electron.), 11(8):587-597.

[2]Duncan-Johnson, C.C., Donchin, E., 1977. On quantifying surprise: the variation of event-related potentials with subjective probability. Psychophysiology, 14(5):456-467.

[3]Farwell, L.A., Donchin, E., 1988. Talking off the top of your head: toward a mental prosthesis utilizing event-related brain potentials. Electroencephal. Clin. Neurophys., 70(6):510-523.

[4]Fazel-Rezai, R., Abhari, K., 2009. A region-based P300 speller for brain-computer interface. Can. J. Electr. Comput. Eng., 34(3):81-85.

[5]Guan, C., Thulasidas, M., Wu, J., 2004. High Performance P300 Speller for Brain-Computer Interface. IEEE Int. Workshop on Biomedical Circuits and Systems, p.S3/5/ INV-S3/13-16.

[6]Guger, C., Daban, S., Sellers, E., Holzner, C., Krausz, G., Carabalona, R., Gramatica, F., Edlinger, G., 2009. How many people are able to control a P300-based brain-computer interface (BCI)? Neurosci. Lett., 462(1):94-98.

[7]Hoffmann, U., Vesin, J.M., Ebrahimi, T., Diserens, K., 2008. An efficient P300-based brain-computer interface for disabled subjects. J. Neurosci. Methods, 167(1):115-125.

[8]Jin, J., Allison, B.Z., Sellers, E.W., Brunner, C., Horki, P., Wang, X.Y., Neuper, C., 2011. An adaptive P300-based control system. J. Neur. Eng., 8(3):036006.

[9]Kaper, M., Meinicke, P., Grossekathoefer, U., Lingner, T., Ritter, H., 2004. BCI competition 2003—data set IIb: support vector machines for the P300 speller paradigm. IEEE Trans. Biomed. Eng., 51(6):1073-1076.

[10]Krusienski, D.J., Sellers, E.W., McFarland, D.J., Vaughan, T.M., Wolpaw, J.R., 2008. Toward enhanced P300 speller performance. J. Neurosci. Methods, 167(1):15-21.

[11]Li, Y., Zhang, J.H., Su, Y., Chen, W.D., Qi, Y., Zhang, J.C., Zheng, X.X., 2009. P300 Based BCI Messenger. IEEE/ICME Int. Conf. on Complex Medical Engineering, p.1-5.

[12]Mak, J.N., Wolpaw, J.R., 2009. Clinical applications of brain-computer interfaces: current state and future prospects. IEEE Rev. Biomed. Eng., 2:187-199.

[13]Mak, J.N., Arbel, Y., Minett, J.W., McCane, L.M., Yuksel, B., Ryan, D., Thompson, D., Bianchi, L., Erdogmus, D., 2011. Optimizing the P300-based brain-computer interface: current status, limitations and future directions. J. Neur. Eng., 8(2):025003.

[14]McFarland, D.J., Sarnacki, W.A., Wolpaw, J.R., 2003. Brain–computer interface (BCI) operation: optimizing information transfer rates. Biol. Psychol., 63(3):237-251.

[15]Picton, T.W., 1992. The P300 wave of the human event-related potential. J. Clin. Neurophysiol., 9(4):456-479.

[16]Pires, G., Castelo-Branco, M., Nunes, U., 2008. Visual P300-Based BCI to Steer a Wheelchair: a Bayesian Approach. 30th Annual Int. IEEE EMBS Conf., p.658-661.

[17]Rakotomarnonjy, A., Guigue, V., 2008. BCI competition III: dataset II—ensemble of SVMs for BCIP300 speller. IEEE Trans. Biomed. Eng., 55(3):1147-1154.

[18]Schalk, G., McFarland, D.J., Hinterberger, T., Birbaumer, N., Wolpaw, J.R., 2004. BCI2000: a general-purpose, brain-computer interface (BCI) system. IEEE Trans. Biomed. Eng., 51(6):1034-1043.

[19]Schlogl, A., Keinrath, C., Zimmermann, D., Scherer, R., Leeb, R., Pfurtscheller, G., 2007. A fully automated correction method of EOG artifacts in EEG recordings. Clin. Neurophys., 118(1):98-104.

[20]Sellers, E.W., Donchin, E., 2006. A P300-based brain-computer interface: initial tests by ALS patients. Clin. Neurophys., 117(3):538-548.

[21]Sellers, E.W., Krusienski, D.J., McFarland, D.J., Vaughan, T.M., Wolpaw, J.R., 2006. A P300 event-related potential brain-computer interface (BCI): the effects of matrix size and inter stimulus interval on performance. Biol. Psychol., 73(3):242-252.

[22]Sellers, E.W., Frye, G.E., Hauser, C.K., Townsend, G., 2011. Suppressing flashes of items surrounding targets during calibration of a P300-based brain-computer interface improves performance. J. Neur. Eng., 8(2):025024.

[23]Townsend, G., LaPallo, B.K., Boulay, C.B., Krusienski, D.J., Frye, G.E., Hauser, C.K., Schwartz, N.E., Vaughan, T.M., Wolpaw, J.R., Sellers, E.W., 2010. A novel P300-based brain-computer interface stimulus presentation paradigm: moving beyond rows and columns. Clin. Neurophys., 121(7):1109-1120.

[24]Vaughan, T.M., McFarland, D.J., Schalk, G., Sarnacki, W.A., Krusienski, D.J., Sellers, E.W., Wolpaw, J.R., 2006. The wadsworth BCI research and development program: at home with BCI. IEEE Trans. Neur. Syst. Rehabil. Eng., 14(2):229-233.

[25]Wolpaw, J.R., Birbaumer, N., McFarland, D.J., Pfurtscheller, G., Vaughan, T.M., 2002. Brain-computer interfaces for communication and control. Clin. Neurophys., 113(6):767-791.

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