JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome

Author(s): Shibin HONG, Xin KANG, Ka U. LIO, Yiping LE, Chuan WANG, Jianhua LIN, Ning ZHANG
Affiliation(s): Department of Obstetrics and Gynecology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China; more
Corresponding email(s): ningning1723@126.com, linjhuarj@126.com
Key Words: Term pregnancy; Eisenmenger syndrome; Severe pulmonary hypertension; Multidisciplinary team (MDT)

Share this article to： More <<< Previous Paper \|Next Paper >>>

Shibin HONG, Xin KANG, Ka U. LIO, Yiping LE, Chuan WANG, Jianhua LIN, Ning ZHANG. Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome[J]. Journal of Zhejiang University Science B, 2023, 24(7): 89-93.

@article{title="Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome",
author="Shibin HONG, Xin KANG, Ka U. LIO, Yiping LE, Chuan WANG, Jianhua LIN, Ning ZHANG",
journal="Journal of Zhejiang University Science B",
volume="24",
number="1",
pages="89-93",
year="2023",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2200368"
}

%0 Journal Article
%T Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome
%A Shibin HONG
%A Xin KANG
%A Ka U. LIO
%A Yiping LE
%A Chuan WANG
%A Jianhua LIN
%A Ning ZHANG
%J Journal of Zhejiang University SCIENCE B
%V 24
%N 1
%P 89-93
%@ 1673-1581
%D 2023
%I Zhejiang University Press & Springer

TY - JOUR
T1 - Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome
A1 - Shibin HONG
A1 - Xin KANG
A1 - Ka U. LIO
A1 - Yiping LE
A1 - Chuan WANG
A1 - Jianhua LIN
A1 - Ning ZHANG
J0 - Journal of Zhejiang University Science B
VL - 24
IS - 1
SP - 89
EP - 93
%@ 1673-1581
Y1 - 2023
PB - Zhejiang University Press & Springer
ER -

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: Pregnancy in patients with Eisenmenger syndrome (ES) is associated with high maternal mortality rates of 30%‒50%, or even up to 65% in the case of a cesarean section (Yuan, 2016). Here, we report a case of term pregnancy complicated with ES and severe pulmonary artery hypertension (PAH), which was managed by a multidisciplinary team (MDT) and resulted in an uncomplicated delivery via elective cesarean section. The goal of this study is to emphasize the importance of multidisciplinary approach in the management of pregnancy with ES, which can profoundly improve maternal and infant outcomes.

足月妊娠合并艾森曼格综合征的多学科治疗

洪士彬^1,2，康昕¹，Ka U.LIO³，乐怡平¹，汪川¹，林建华¹，张宁^1,2
¹上海交通大学医学院附属仁济医院妇产科，中国上海市，200127
²上海交通大学医学院附属仁济医院上海市妇科肿瘤重点实验室，中国上海市，200127
³天普大学医院内科，美国宾夕法尼亚，19140
概要：妊娠合并心脏病的发病率为0.5%~3.0%，是导致孕产妇死亡的非产科病因首位。而重度肺动脉高压的处理最为棘手，合并艾森曼格综合征的孕产妇死亡率高达30%~50%，剖宫产患者甚至达65%~75%。妊娠合并重度肺动脉高压属于妊娠禁忌，一旦诊断需尽快终止妊娠，能达足月妊娠者临床非常罕见。本文报道一例足月妊娠合并重度肺动脉高压和艾森曼格综合征患者的成功诊治，旨在提高产科医师对该合并症的重视和多学科管理，并提高对该疾病围手术期的精细诊疗水平。

关键词组：足月妊娠；艾森曼格综合征；重度肺动脉高压；多学科团队(MDT)

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]BallardW III, DixonB, McEvoyCA, et al., 2021. Pulmonary arterial hypertension in pregnancy. Cardiol Clin, 39(1):109-118.

[2]KarsentyC, WaldmannV, MulderB, et al., 2021. Thromboembolic complications in adult congenital heart disease: the knowns and the unknowns. Clin Res Cardiol, 110(9):1380-1391.

[3]LopezBM, MalhaméI, DaviesLK, et al., 2020. Eisenmenger syndrome in pregnancy: a management conundrum. J Cardiothorac Vasc Anesth, 34(10):2813-2822.

[4]MaciejewskiT, DarochaT, KiermaszK, et al., 2019. Emergency caesarean section delivery and puerperium in a patient with severe idiopathic pulmonary arterial hypertension—a case report. Anaesthesiol Intensive Ther, 51(1):‍70-71.

[5]Regitz-ZagrosekV, Roos-HesselinkJW, BauersachsJ, et al., 2018. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy: the Task Force for the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J, 39(34):3165-3241.

[6]Schaefer-ProkopC, ProkopM, 2008. CTPA for the diagnosis of acute pulmonary embolism during pregnancy. Eur Radiol, 18(12):2705-2708.

[7]SimonneauG, MontaniD, CelermajerDS, et al., 2019. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respir J, 53:1801913.

[8]SlaibiA, IbraheemB, MohannaF, 2021. Challenging management of a pregnancy complicated by eisenmenger syndrome; a case report. Ann Med Surg (Lond), 69:102721.

[9]YangJZ, FernandesTM, KimNH, et al., 2021. Pregnancy and pulmonary arterial hypertension: a case series and litera

[10]ture review. Am J Obstet Gynecol MFM, 3(4):100358.

[11]YuanSM, 2016. Eisenmenger syndrome in pregnancy. Braz J Cardiovasc Surg, 31(4):325-329.

[12]ZhangJL, LuJK, ZhouXR, et al., 2018. Perioperative management of pregnant women with idiopathic pulmonary arterial hypertension: an observational case series study from China. J Cardiothorac Vasc Anesth, 32(6):‍2547-2559.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

- Go to

足月妊娠合并艾森曼格综合征的多学科治疗

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference