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SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal-hippocampal neural encoding of movement initiation and place fields during goal-directed navigation
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Jin SHAN1,2, Wei XU1,2, Jinping LUO1,2, Yaoyao LIU1,2, Ming LI1,2, Luyi JING1,2, Yu WANG1,2, Shiya LV1,2, Zhaojie XU1,2, Juntao LIU1,2, Yiming DUAN1,2, Qianli JIA1,2, Yilin SONG1,2, Mixia WANG1,2, Xinxia CAI1,2. SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal-hippocampal neural encoding of movement initiation and place fields during goal-directed navigation[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal-hippocampal neural encoding of movement initiation and place fields during goal-directed navigation",
author="Jin SHAN1,2, Wei XU1,2, Jinping LUO1,2, Yaoyao LIU1,2, Ming LI1,2, Luyi JING1,2, Yu WANG1,2, Shiya LV1,2, Zhaojie XU1,2, Juntao LIU1,2, Yiming DUAN1,2, Qianli JIA1,2, Yilin SONG1,2, Mixia WANG1,2, Xinxia CAI1,2",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2500462"
}
%0 Journal Article
%T SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal-hippocampal neural encoding of movement initiation and place fields during goal-directed navigation
%A Jin SHAN1
%A 2
%A Wei XU1
%A 2
%A Jinping LUO1
%A 2
%A Yaoyao LIU1
%A 2
%A Ming LI1
%A 2
%A Luyi JING1
%A 2
%A Yu WANG1
%A 2
%A Shiya LV1
%A 2
%A Zhaojie XU1
%A 2
%A Juntao LIU1
%A 2
%A Yiming DUAN1
%A 2
%A Qianli JIA1
%A 2
%A Yilin SONG1
%A 2
%A Mixia WANG1
%A 2
%A Xinxia CAI1
%A 2
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2500462
TY - JOUR
T1 - SWCNTs/PEDOT:PSS-modified microelectrode arrays reveal striatal-hippocampal neural encoding of movement initiation and place fields during goal-directed navigation
A1 - Jin SHAN1
A1 - 2
A1 - Wei XU1
A1 - 2
A1 - Jinping LUO1
A1 - 2
A1 - Yaoyao LIU1
A1 - 2
A1 - Ming LI1
A1 - 2
A1 - Luyi JING1
A1 - 2
A1 - Yu WANG1
A1 - 2
A1 - Shiya LV1
A1 - 2
A1 - Zhaojie XU1
A1 - 2
A1 - Juntao LIU1
A1 - 2
A1 - Yiming DUAN1
A1 - 2
A1 - Qianli JIA1
A1 - 2
A1 - Yilin SONG1
A1 - 2
A1 - Mixia WANG1
A1 - 2
A1 - Xinxia CAI1
A1 - 2
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2500462
Abstract: Goal-directed navigation necessitates coordinated interactions among multiple brain regions, with the hippocampus and striatum playing critical roles in spatial representation, movement-related information, and reward-related evaluation. The hippocampus, particularly the CA1 (Cornu Ammonis 1) region, is renowned for its role in spatial encoding via place cells. The striatum, a basal ganglia nucleus, can integrate cortical, thalamic, and limbic inputs to regulate motor planning, reward valuation, and behavioral flexibility. Despite extensive research, a key challenge remains: the lack of high spatiotemporal resolution, high-precision, and multi-channel electrodes that are structurally matched for reliable implantation across multiple brain regions. To address this, we developed two silicon-based microelectrode arrays (MEAs) anatomically tailored for dual-region neuronal electrophysiological recording of the striatum and CA1. By modifying the electrode sites with SWCNTs/PEDOT:PSS nanocomposites, we significantly enhanced the electrical performance, reducing impedance and phase delay. Leveraging this platform, we demonstrated that neurons in the rat ventral striatum (vStr) contribute to movement initiation, transmitting information to CA1, while CA1 place cells dynamically encode new goal locations and relay spatial information to neurons in the dorsal striatum (dStr). This research provides a reliable platform for exploring the neural interactions between the striatum and hippocampus, establishing a foundation for future studies on neural circuits in complex behaviors.
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