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Journal of Zhejiang University SCIENCE A 2000 Vol.1 No.2 P.190-195

http://doi.org/10.1631/jzus.2000.0190


HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION


Author(s):  Sorsa Sota Solomon, FAN De-fang, LI Shao-nan

Affiliation(s):  Institute of Pesticide Environmental Toxicology, Department of Plant Protection, Huajiachi Campus of Zhejiang University, Hangzhou 310029, China

Corresponding email(s): 

Key Words:  fenitrothion, hepatic GST activity, glutathione S-transferase, fish


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Sorsa Sota Solomon, FAN De-fang, LI Shao-nan. HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION[J]. Journal of Zhejiang University Science A, 2000, 1(2): 190-195.

@article{title="HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION",
author="Sorsa Sota Solomon, FAN De-fang, LI Shao-nan",
journal="Journal of Zhejiang University Science A",
volume="1",
number="2",
pages="190-195",
year="2000",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2000.0190"
}

%0 Journal Article
%T HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION
%A Sorsa Sota Solomon
%A FAN De-fang
%A LI Shao-nan
%J Journal of Zhejiang University SCIENCE A
%V 1
%N 2
%P 190-195
%@ 1869-1951
%D 2000
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2000.0190

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T1 - HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION
A1 - Sorsa Sota Solomon
A1 - FAN De-fang
A1 - LI Shao-nan
J0 - Journal of Zhejiang University Science A
VL - 1
IS - 2
SP - 190
EP - 195
%@ 1869-1951
Y1 - 2000
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2000.0190


Abstract: 
Two common fish species, mosquitofish (Gambusia affinis) and topmouth gudgeon (Pseudorasobora parva ) were exposed to different concentrations of fenitrothion in static system for 96 h. Hepatic glutathione S-transferase activity was evaluated after 48 and 96 h pesticide exposure, and was also examined in fish pretreated with pepironyl butoxide and triphenyl phosphate and then exposed to fenitrothion. Results indicated presence of intense glutathione S-transferase activity in both species, mosquitofish exhibiting the higher activity. In both species the activity decreased as the concentration of fenitrothion increased, topmouth gudgeon being more susceptible than mosquitofish. In mosquitofish pretreated with pepironyl butoxide, glutathione S-transferase activity was increased (11.8%) comparded with the control but in topmouth gudgeon it was decreased (21.6%) at the end of 96 h. glutathione S-transferase activity was significantly reduce in both species pretreated with triphenyl phosphate at the end of 96 h exposure, topmouth gudgeon being highly susceptible.

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