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Journal of Zhejiang University SCIENCE A 2004 Vol.5 No.8 P.941~949


Study on properties of residue-residue contacts in protein

Author(s):  WANG Xiang-hong, KE Jian-hong, ZHEN Yi-zhuang, CHEN Ai, XU Yin-xiang

Affiliation(s):  Department of Physics, Wenzhou Normal College, Wenzhou 325000, China

Corresponding email(s):   wangxh@wznc.zj.cn

Key Words:  Globular protein, Structural class, Residue distance, Long- and short-range contact

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WANG Xiang-hong, KE Jian-hong, ZHEN Yi-zhuang, CHEN Ai, XU Yin-xiang. Study on properties of residue-residue contacts in protein[J]. Journal of Zhejiang University Science A, 2004, 5(8): 941~949.

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%I Zhejiang University Press & Springer
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T1 - Study on properties of residue-residue contacts in protein
A1 - WANG Xiang-hong
A1 - KE Jian-hong
A1 - ZHEN Yi-zhuang
A1 - CHEN Ai
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Y1 - 2004
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2004.0941

Residue-residue contacts are very important in forming protein structure. In this work, we calculated the average probability of residue-residue contacts in 470 globular proteins and analyzed the distribution of contacts in the different interval of residues using Contacts of Structural Units (CSU) and structural classification (SCOP) software. It was found that the relationship between the average probability P̄L and the residue distance L for four structural classes of proteins could be expressed as lgPL=a+b×L, where a and b are coefficients. We also discussed the connection between two aspects of proteins which have equal array residue number and found that the distribution probability was stable (or unstable) if the proteins had the same (or different) compact (for example synthase) in the same structural class.

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