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Journal of Zhejiang University SCIENCE B 2005 Vol.6 No.9 P.897~902

http://doi.org/10.1631/jzus.2005.B0897


Resistin levels of serum and follicular fluid in non-obese patients with polycystic ovary syndrome during IVF cycles


Author(s):  LU Xiu-e, HUANG He-feng, LI Mei-gen, ZHU Yi-min, QIANG Yu-li, DONG Min-yue

Affiliation(s):  Women’ more

Corresponding email(s):   loulu63@sohu.com, Huanghefg@hotmail.com

Key Words:  Insulin resistance, Resistin, In vitro fertilization-embryo transfer, Polycystic ovary syndrome


LU Xiu-e, HUANG He-feng, LI Mei-gen, ZHU Yi-min, QIANG Yu-li, DONG Min-yue. Resistin levels of serum and follicular fluid in non-obese patients with polycystic ovary syndrome during IVF cycles[J]. Journal of Zhejiang University Science B, 2005, 6(9): 897~902.

@article{title="Resistin levels of serum and follicular fluid in non-obese patients with polycystic ovary syndrome during IVF cycles",
author="LU Xiu-e, HUANG He-feng, LI Mei-gen, ZHU Yi-min, QIANG Yu-li, DONG Min-yue",
journal="Journal of Zhejiang University Science B",
volume="6",
number="9",
pages="897~902",
year="2005",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2005.B0897"
}

%0 Journal Article
%T Resistin levels of serum and follicular fluid in non-obese patients with polycystic ovary syndrome during IVF cycles
%A LU Xiu-e
%A HUANG He-feng
%A LI Mei-gen
%A ZHU Yi-min
%A QIANG Yu-li
%A DONG Min-yue
%J Journal of Zhejiang University SCIENCE B
%V 6
%N 9
%P 897~902
%@ 1673-1581
%D 2005
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2005.B0897

TY - JOUR
T1 - Resistin levels of serum and follicular fluid in non-obese patients with polycystic ovary syndrome during IVF cycles
A1 - LU Xiu-e
A1 - HUANG He-feng
A1 - LI Mei-gen
A1 - ZHU Yi-min
A1 - QIANG Yu-li
A1 - DONG Min-yue
J0 - Journal of Zhejiang University Science B
VL - 6
IS - 9
SP - 897
EP - 902
%@ 1673-1581
Y1 - 2005
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2005.B0897


Abstract: 
Objectives: To measure serum and follicular resistin, steroids hormone levels in women with PCOS (polycystic ovary syndrome) (BMI (body mass index)<25 kg/m2), to assess possible correlations of resistin to hormonal and metabolic parameters and to analyze the clinical outcomes of in vitro fertilization-embryo transfer (IVF-ET) in women with PCOS and tubal infertility. Study design: We analyzed the clinical outcomes of IVF-ET in women with PCOS (BMI<25 kg/m2) and tubal infertility during the years 2002 to 2004 and compared the serum and follicular fluid resistin levels, estradiol (E2), progesterone (P), testosterone (T) levels in 20 PCOS and 20 healthy, age-matched women without PCOS during IVF-stimulated cycles. The correlations between the resistin levels and the outcomes of IVF-ET were evaluated. Results: No significant differences in resistin levels of either serum or follicular fluid between PCOS and control group were found. However, resistin levels in serum were higher than that in follicular fluid in both groups. Multiple regression analysis showed that resistin levels in serum did not correlate with BMI, estradiol, LH (luteinizing hormone) and insulin level in fasting blood. No significant correlations were found between follicular fluid reisistin levels and fertilization rate, implantation rate, clinical pregnancy rate or early miscarriage rate in both PCOS and control groups. Conclusion: Our results show that resistin does not have correlation with the hormonal and metabolic parameters as well as the outcomes of IVF. These data suggest that resistin is unlikely to be a local determinant factor in steroidogenesis and growth and maturation of oocytes during IVF-ET in lean women with PCOS.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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