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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.8 P.575~579

10.1631/jzus.2007.B0575


Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention


Author(s):  ZHOU Bin-quan, TAHK Seung-Jea

Affiliation(s):  Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China; more

Corresponding email(s):   zhoubq@hotmail.com

Key Words:  Acute myocardial infarction (AMI), Distal protection device, Percutaneous coronary intervention (PCI)


ZHOU Bin-quan, TAHK Seung-Jea. Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention[J]. Journal of Zhejiang University Science B, 2007, 8(8): 575~579.

@article{title="Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention",
author="ZHOU Bin-quan, TAHK Seung-Jea",
journal="Journal of Zhejiang University Science B",
volume="8",
number="8",
pages="575~579",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.B0575"
}

%0 Journal Article
%T Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention
%A ZHOU Bin-quan
%A TAHK Seung-Jea
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 8
%P 575~579
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer

TY - JOUR
T1 - Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention
A1 - ZHOU Bin-quan
A1 - TAHK Seung-Jea
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 8
SP - 575
EP - 579
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -


Abstract: 
Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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