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CLC number: R51

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Received: 2009-07-21

Revision Accepted: 2009-10-22

Crosschecked: 2009-11-16

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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.12 P.933-936


Bacteremia due to Rhodococcus equi: a case report and review of the literature

Author(s):  Xi-yuan CHEN, Feng XU, Jing-yan XIA, Yu-sheng CHENG, Yan YANG

Affiliation(s):  Department of Respiratory Medicine, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; more

Corresponding email(s):   xufeng99@yahoo.com

Key Words:  Rhodococcus equi, Bacteremia, Opportunistic pathogen

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Xi-yuan CHEN, Feng XU, Jing-yan XIA, Yu-sheng CHENG, Yan YANG. Bacteremia due to Rhodococcus equi: a case report and review of the literature[J]. Journal of Zhejiang University Science B, 2009, 10(12): 933-936.

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%A Jing-yan XIA
%A Yu-sheng CHENG
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T1 - Bacteremia due to Rhodococcus equi: a case report and review of the literature
A1 - Xi-yuan CHEN
A1 - Feng XU
A1 - Jing-yan XIA
A1 - Yu-sheng CHENG
A1 - Yan YANG
J0 - Journal of Zhejiang University Science B
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0920214

Rhodococcus equi, previously known as Corynebacterium equi, is one of the most important causes of zoonotic infections in grazing animals. Increased cases of human infection with R. equi have been reported, especially in immunocompromised patients, within recent years. We present a case of R. equi bacteremia in a 51-year-old man with diabetes and liver cirrhosis, on long-term corticosteroid therapy after skin-grafting surgery. The patient recovered soon after he was treated with vancomycin. This review focuses on the microbiological characteristics of this organism, and the diagnosis and treatment of this infection.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Alonso, P., Tashima, K.T., Goldstein, I.J., 2001. Disseminated Rhodococcus equi infection. Clin. Infect. Dis., 32(6): 970-971.

[2] Cronin, S.M., Abidi, M.H., Shearer, C.J., Chandrasekar, P.H., Ibrahim, R.B., 2008. Rhodococcus equi lung infection in an allogeneic hematopoietic stem cell transplant recipient. Transpl. Infect. Dis., 10(1):48-51.

[3] Golub, B., Falk, G., Spink, W.W., 1967. Lung abscess due to Corynebacterium equi. Report of first human infection. Ann. Intern. Med., 66(6):1174-1177.

[4] Kamboj, M., Kalra, A., Kak, V., 2005. Rhodococcus equi brain abscess in a patient without HIV. J. Clin. Pathol., 58(4): 423-425.

[5] Kedlaya, I., Ing, M.B., Wong, S.S., 2001. Rhodococcus equi infections in immunocompetent hosts: case report and review. Clin. Infect. Dis., 32(3):39-46.

[6] Ladrón, N., Fernández, M., Aguero, J., Zörn, B.G., Vázquez-Boland, J.A., Navas, J., 2003. Rapid identification of Rhodococcus equi by a PCR assay targeting the choE gene. J. Clin. Microbiol., 41(7):3241-3245.

[7] Lipsky, B.A., Goldberger, A.C., Tompkins, L.S., Plorde, J.J., 1982. Infections caused by nondiphtheria corynebacteria. Rev. Infect. Dis., 4(6):1220-1235.

[8] Marchiori, E., de Mendonça, R.G., Capone, D., de Cerqueira, E.M., Souza Júnior, A.S., Zanetti, G., Escuissato, D., Gasparetto, E., 2006. Rhodococcus equi infection in acquired immunodeficiency syndrome. Computed tomography aspects. J. Bras. Pneumol., 32(5):405-409.

[9] Perez, M.G., Vassilev, T., Kemmerly, S.A., 2002. Rhodococcus equi infection in transplant recipients: a case of mistaken identity and review of the literature. Transpl. Infect. Dis., 4(1):52-56.

[10] Prescott, J.F., 1991. Rhodococcus equi: an animal and human pathogen. Clin. Microbiol. Rev., 4(1):20-34.

[11] Puthucheary, S.D., Sangkar, V., Hafeez, A., Karunakaran, R., Raja, N.S., Hassan, H.H., 2006. Rhodococcus equi―an emerging human pathogen in immunocompromized hosts: a report of four cases from Malaysia. Southeast Asian J. Trop. Med. Public Health, 37(1):157-161.

[12] Roda, R.H., Young, M., Timpone, J., Rosen, J., 2009. Rhodococcus equi pulmonary-central nervous system syndrome: brain abscess in a patient on high-dose steroids-a case report and review of the literature. Diagn. Microbiol. Infect. Dis., 63(1):96-99.

[13] Torres-Tortosa, M., Arrizabalaga, J., Villanueva, J.L., Gálvez, J., Leyes, M., Valencia, M.E., Flores, J., Peña, J.M., Pérez-Cecilia, E., Quereda, C., 2003. Prognosis and clinical evaluation of infection caused by Rhodococcus equi in HIV-infected patients. A multicenter study of 67 cases. Chest, 123(6):1970-1976.

[14] Tse, K.C., Tang, S.C., Chan, T.M., Lan, K.N., 2008. Rhodococcus lung abscess complicating kidney transplantation: successful management by combination antibiotic therapy. Transpl. Infect. Dis., 10(1):44-47.

[15] Wagner, D., Joseph, J., Huang, J., Xu, H., 2007. Malakoplakia of the prostate on needle core biopsy: a case report and review of the literature. Int. J. Surg. Pathol., 15(1):86-89.

[16] Weinstock, D.M., Brown, A.E., 2002. Rhodococcus equi: an emerging pathogen. Clin. Infect. Dis., 34(10):1379-1385.

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