JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B 2008 Vol.9 No.1 P.39-43

Breast metastasis from small cell lung carcinoma

Author(s): Shi-ping LUH, Chih KUO, Thomas Chang-yao TSAO
Affiliation(s): Department of Surgery, Chia-Yi Christian Hospital and Chung-Shan Medical University and Hospital, Taichung 402, Taiwan, China; more
Corresponding email(s): luh572001@yahoo.com.tw
Key Words: Small cell carcinoma, Breast metastasis, Lung

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Abstract: Breast metastases from extramammary neoplasms are very rare. We presented a 66 year-old female with metastasis of small cell lung carcinoma to the breast. She presented with consolidation over the left upper lobe of her lung undetermined after endobronchial or video-assisted thoracoscopic surgery (VATS) biopsy, and this was treated effectively after antibiotic therapy at initial stage. The left breast lumps were noted 4 months later, and she underwent a modified radical mastectomy under the impression of primary breast carcinoma. However, the subsequent chest imaging revealed re-growing mass over the left mediastinum and hilum, and cells with the same morphological and staining features were found from specimens of transbronchial brushing and biopsy. An accurate diagnosis to distinguish a primary breast carcinoma from metastatic one is very important because the therapeutic planning and the outcome between them are different.

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