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Journal of Zhejiang University SCIENCE A 2004 Vol.5 No.2 P.186-192


A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway

Author(s):  LIN Xin-da, LIN Xin-hua, CHENG Jia-an

Affiliation(s):  Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China; more

Corresponding email(s):   linxinda@yahoo.com, linxh@uc.edu, jacheng@sun.zju.edu.cn

Key Words:  Drosophila, Genetic screen, Wingless signal transduction, Mutant allele


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LIN Xin-da, LIN Xin-hua, CHENG Jia-an. A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway[J]. Journal of Zhejiang University Science A, 2004, 5(2): 186-192.

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T1 - A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway
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DOI - 10.1631/jzus.2004.0186

A wing specific F1 genetic screen was carried out using the powerfuldrosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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