Full Text:   <2677>

CLC number: TQ028.3

On-line Access: 

Received: 2005-09-27

Revision Accepted: 2005-12-10

Crosschecked: 0000-00-00

Cited: 4

Clicked: 5547

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
1. Reference List
Open peer comments

Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.7 P.559-564


Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed

Author(s):  LÜ, Yu-bin, YANG Yi-wen, WU Ping-dong

Affiliation(s):  National Laboratory of Secondary Resources Chemical Engineering, Zhejiang University, Hangzhou 310027, China

Corresponding email(s):   lvyubin2001@zju.edu.cn, wupd@zju.edu.cn

Key Words:  Simulated moving bed (SMB), Separation, Soybean phosphatidylcholine (PC)

LÜ Yu-bin, YANG Yi-wen, WU Ping-dong. Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed[J]. Journal of Zhejiang University Science B, 2006, 7(7): 559-564.

@article{title="Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed",
author="LÜ Yu-bin, YANG Yi-wen, WU Ping-dong",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
%A Yu-bin
%A YANG Yi-wen
%A WU Ping-dong
%J Journal of Zhejiang University SCIENCE B
%V 7
%N 7
%P 559-564
%@ 1673-1581
%D 2006
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0559

T1 - Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
A1 - LÜ
A1 - Yu-bin
A1 - YANG Yi-wen
A1 - WU Ping-dong
J0 - Journal of Zhejiang University Science B
VL - 7
IS - 7
SP - 559
EP - 564
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2006.B0559

A simulated moving bed (SMB), equipped with eight silica-gel columns, was used to separate phosphatidylcholine (PC) from soybean phospholipids. The effects of flow rate in Sections 2 (Q2) and 3 (Q3), switching time, feed flow rate and feed concentration on the operating performance parameters: purity, recovery, productivity and desorbent consumption were studied. Operating conditions leading to more than 90% purity in both outlet streams have been identified, together with those achieving optimal performance. Regions leading to complete separation are observed and explained theoretically. As the mass-transfer effect was not considered, the triangle theory only gives initial guesses for the optimal operating conditions.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Amari, J.V., Brown, P.R., 1990. Isolation and purification of lecithin by preparative high-performance liquid chromatography. Journal of Chromatography A, 517(1):219-228.

[2] Bruce, P., 1998. Simulated moving bed processing: escape from the high-cost box. Journal of Chromatography A, 827:43-160.

[3] Jupke, A., Epping, A., Schmidt-Traub, H., 2002. Optimal design of batch and simulated moving bed chromatographic separation processes. Journal of Chromatography A, 944(1-2):93-117.

[4] Li, Y., 2004. A Study of Analysis and Purification of Soybean Phosphatidylcholine. Master Thesis, Zhejiang University, Hangzhou (in Chinese).

[5] Mazzotti, M., Storti, G., Morbidelli, M., 1997. Optimal operation of simulated moving bed units for nonlinear chromatographic separations. Journal of Chromatography A, 769(1):3-24.

[6] Meeren, P.V., Vanderdeelen, J., Huys, M., Baert, L., 1990. Optimization of the column load ability for the preparative HPLC separation of soybean phospholipids. JAOCS, 67:815-820.

[7] Migliorini, C., Mazzotti, M., Morbidelli, M., 1998. Continuous chromatographic separation through simulated moving beds under linear and nonlinear conditions. Journal of Chromatography A, 827(2):161-173.

[8] Ruthven, D.M., 1984. Principles of Adsorption and Adsorption Processes. Wiley, New York, p.380-409.

[9] Ruthven, D.M., Ching, C.B., 1989. Counter-current and simulated counter-current adsorption separation process. Chemical Engineering Science, 44(5):1011-1038.

[10] Storti, G., Mazzotti, M., Morbidelli, M., Carra, S., 1993. Robust design of binary countercurrent adsorption separation processes. AICHE J., 39(3):471-492.

Open peer comments: Debate/Discuss/Question/Opinion


Kevin Lopez@UNAM<kevinlopez\_qfb@hotmail.com>

2013-10-29 04:29:24

thanks for your help in my research

Please provide your name, email address and a comment

Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE