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CLC number: TQ028.3

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Received: 2005-09-27

Revision Accepted: 2005-12-10

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Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.7 P.559~564


Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed

Author(s):  LÜ, Yu-bin, YANG Yi-wen, WU Ping-dong

Affiliation(s):  National Laboratory of Secondary Resources Chemical Engineering, Zhejiang University, Hangzhou 310027, China

Corresponding email(s):   lvyubin2001@zju.edu.cn, wupd@zju.edu.cn

Key Words:  Simulated moving bed (SMB), Separation, Soybean phosphatidylcholine (PC)

LÜ Yu-bin, YANG Yi-wen, WU Ping-dong. Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed[J]. Journal of Zhejiang University Science B, 2006, 7(7): 559~564.

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journal="Journal of Zhejiang University Science B",
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%T Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
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%J Journal of Zhejiang University SCIENCE B
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%DOI 10.1631/jzus.2006.B0559

T1 - Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
A1 - LÜ
A1 - Yu-bin
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A1 - WU Ping-dong
J0 - Journal of Zhejiang University Science B
VL - 7
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EP - 564
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DOI - 10.1631/jzus.2006.B0559

A simulated moving bed (SMB), equipped with eight silica-gel columns, was used to separate phosphatidylcholine (PC) from soybean phospholipids. The effects of flow rate in Sections 2 (Q2) and 3 (Q3), switching time, feed flow rate and feed concentration on the operating performance parameters: purity, recovery, productivity and desorbent consumption were studied. Operating conditions leading to more than 90% purity in both outlet streams have been identified, together with those achieving optimal performance. Regions leading to complete separation are observed and explained theoretically. As the mass-transfer effect was not considered, the triangle theory only gives initial guesses for the optimal operating conditions.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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[6] Meeren, P.V., Vanderdeelen, J., Huys, M., Baert, L., 1990. Optimization of the column load ability for the preparative HPLC separation of soybean phospholipids. JAOCS, 67:815-820.

[7] Migliorini, C., Mazzotti, M., Morbidelli, M., 1998. Continuous chromatographic separation through simulated moving beds under linear and nonlinear conditions. Journal of Chromatography A, 827(2):161-173.

[8] Ruthven, D.M., 1984. Principles of Adsorption and Adsorption Processes. Wiley, New York, p.380-409.

[9] Ruthven, D.M., Ching, C.B., 1989. Counter-current and simulated counter-current adsorption separation process. Chemical Engineering Science, 44(5):1011-1038.

[10] Storti, G., Mazzotti, M., Morbidelli, M., Carra, S., 1993. Robust design of binary countercurrent adsorption separation processes. AICHE J., 39(3):471-492.

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Kevin Lopez@UNAM<kevinlopez\_qfb@hotmail.com>

2013-10-29 04:29:24

thanks for your help in my research

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