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On-line Access: 2023-11-13

Received: 2023-05-18

Revision Accepted: 2023-07-16

Crosschecked: 2023-11-14

Cited: 0

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Citations:  Bibtex RefMan EndNote GB/T7714


Ning HU


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Journal of Zhejiang University SCIENCE A 2023 Vol.24 No.11 P.1017-1026


Advances in micro-nano biosensing platforms for intracellular electrophysiology

Author(s):  Jiajin XUE, Min SHAO, Zhigang GAO, Ning HU

Affiliation(s):  General Surgery Department, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou 310052, China; more

Corresponding email(s):   ebwk@zju.edu.cn, huning@zju.edu.cn

Key Words:  Intracellular electrophysiology, Micro-nano biosensing platforms, Cardiology and neuroscience, Intracellular action potentials

Jiajin XUE, Min SHAO, Zhigang GAO, Ning HU. Advances in micro-nano biosensing platforms for intracellular electrophysiology[J]. Journal of Zhejiang University Science A, 2023, 24(11): 1017-1026.

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%A Jiajin XUE
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%A Ning HU
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T1 - Advances in micro-nano biosensing platforms for intracellular electrophysiology
A1 - Jiajin XUE
A1 - Min SHAO
A1 - Zhigang GAO
A1 - Ning HU
J0 - Journal of Zhejiang University Science A
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.A2300267

The establishment of a dependable electrophysiological detection platform is paramount for cardiology and neuroscience research. In the past decade, devices based on micro and nanoscale sensing and control technologies have been developed to construct electrophysiological platforms. Their unique morphological advantages and novel processing methods offer the potential for high-throughput, high-fidelity electrical signal recording. In this review, we analyze the structure, transmembrane strategies, and electrophysiological detection methods of active/passive micro and nano sensing platforms. We also provide an outlook on their vast potential for development in light of the opportunities and challenges facing micro and nano sensing technology, with the aim of pushing for higher-level electrophysiological platform construction to meet the needs of experimental research and clinical applications.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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