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CLC number: R739.6

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Received: 2009-03-11

Revision Accepted: 2009-08-13

Crosschecked: 2009-08-14

Cited: 9

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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.9 P.707~710

10.1631/jzus.B0920071


Subglottic adenoid cystic carcinoma mistaken for asthma


Author(s):  Hua-lin WANG, Lin XU, Fu-jun LI

Affiliation(s):  Department of Otorhinolaryngology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   hzwhl@hotmail.com

Key Words:  Subglottic adenoid cystic carcinoma, Larynx, Asthma


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Hua-lin WANG, Lin XU, Fu-jun LI. Subglottic adenoid cystic carcinoma mistaken for asthma[J]. Journal of Zhejiang University Science B, 2009, 10(9): 707~710.

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T1 - Subglottic adenoid cystic carcinoma mistaken for asthma
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DOI - 10.1631/jzus.B0920071


Abstract: 
Adenoid cystic carcinoma rarely occurs within the subglottic larynx. In this study, a case of subglottic adenoid cystic carcinoma was reported. A 54 year-old Chinese woman developed a sudden onset of chest distress and cough worsening after physical exertion, and was diagnosed with, and treated as, bronchial asthma. Regular anti-asthmatic therapy did not improve the symptoms. Until a sudden dyspnea, a cervicothoracic computerized tomography (CT) revealed that her upper airway was obstructed by a laryngeal tumor. The patient was diagnosed with a subglottic adenoid cystic carcinoma and treated with complete surgical excision and adjuvant radiation therapy. Follow-up endoscopy and laryngeal magnetic resonance imaging (MRI) at six months showed no recurrence of the tumor. The diagnosis of subglottic adenoid cystic carcinoma should be considered in patients who are characterized by dyspnea, cough, and stridor, but do not respond to regular anti-asthmatic therapy.

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