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CLC number: R735.5

On-line Access: 2011-05-06

Received: 2010-09-16

Revision Accepted: 2010-11-03

Crosschecked: 2011-04-10

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.5 P.381-384

http://doi.org/10.1631/jzus.B1000338


Malignant peritoneal mesothelioma presenting with persistent high fever


Author(s):  Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang

Affiliation(s):  Department of Family Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China, Department of Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   hsh0906@163.com

Key Words:  Malignant peritoneal mesothelioma, High fever, Metastasis


Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang. Malignant peritoneal mesothelioma presenting with persistent high fever[J]. Journal of Zhejiang University Science B, 2011, 12(5): 381-384.

@article{title="Malignant peritoneal mesothelioma presenting with persistent high fever",
author="Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang",
journal="Journal of Zhejiang University Science B",
volume="12",
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pages="381-384",
year="2011",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1000338"
}

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%T Malignant peritoneal mesothelioma presenting with persistent high fever
%A Li-ying Chen
%A Ling-xiu Huang
%A Jin Wang
%A Yi Qian
%A Li-zheng Fang
%J Journal of Zhejiang University SCIENCE B
%V 12
%N 5
%P 381-384
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000338

TY - JOUR
T1 - Malignant peritoneal mesothelioma presenting with persistent high fever
A1 - Li-ying Chen
A1 - Ling-xiu Huang
A1 - Jin Wang
A1 - Yi Qian
A1 - Li-zheng Fang
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 5
SP - 381
EP - 384
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000338


Abstract: 
malignant peritoneal mesothelioma (MPM) is a rare tumor that develops in the peritoneum. In this paper, we describe an extremely rare case of MPM metastasizing to the appendix in a 48-year-old female who initially presented with a persistent high fever. The woman reported a slight lower abdominal discomfort which had been relieved by urination for four months. She had lost 5 kg of weight. There was no nausea, vomiting, diarrhea, abdominal pain, or abdominal distension. Many broad spectrum antibiotics were given without relief of fever. Computed tomography (CT) scans revealed a thickened omentum majus and diffused multiple omental nodules. An omentectomy, appendectomy, and adnexectomy were carried out. A gross pathologic specimen of omentum tissue revealed a firm gray-white mass. Microscopic and immunohistochemical examinations confirmed the diagnosis of appendiceal and bilateral adnexal metastases of an MPM. These results suggest that MPM should be considered in the differential diagnosis of unexplained persistent high fever. Awareness of such atypical presentations of mesothelioma may help to make a correct diagnosis.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1]Chua, T.C., Yan, T.D., Morris, D.L., 2009. Peritoneal mesothelioma: current understanding and management. Can. J. Surg., 52(1):59-64.

[2]de Pangher Manzini, V., 2005. Malignant peritoneal mesothelioma. Tumori, 91(1):1-5.

[3]Eltabbakh, G.H., Piver, M.S., Hempling, R.E., Recio, F.O., Intengen, M.E., 1999. Clinical picture, response to therapy, and survival of women with diffuse malignant peritoneal mesothelioma. J. Surg. Oncol., 70(1):6-12.

[4]Feldman, A.L., Libutti, S.K., Pingpank, J.F., Bartlett, D.L., Beresnev, T.H., Mavroukakis, S.M., Steinberg, S.M., Liewehr, D.J., Kleiner, D.E., Alexander, H.R., 2003. Analysis of factors associated with outcome in patients with malignant peritoneal mesothelioma undergoing surgical debulking and intraperitoneal chemotherapy. J. Clin. Oncol., 21(24):4560-4567.

[5]Kerrigan, S.A., Cagle, P., Churg, A., 2003. Malignant mesothelioma of the peritoneum presenting as an inflammatory lesion: a report of four cases. Am. J. Surg. Pathol., 27(2):248-253.

[6]Le, D.T., Deavers, M., Hunt, K., Malpica, A., Verschraegen, C.F., 2003. Cisplatin and irinotecan (CPT-11) for peritoneal mesothelioma. Cancer Invest., 21(5):682-689.

[7]Marchevsky, A.M., 2008. Application of immunohistochemistry to the diagnosis of malignant mesothelioma. Arch. Pathol. Lab. Med., 132(3):397-401.

[8]Markman, M., Kelsen, D., 1992. Efficacy of cisplatin-based intraperitoneal chemptherapy as treatment of malignant peritoneal mesothelioma. J. Cancer Res. Clin. Oncol., 118(7):547-550.

[9]Miller, J., Wynn, W.H., 1908. A malignant tumor arising from the endothelium of the peritoneum, and producing a mucoid ascitic fluid. J. Pathol. Bacteriol., 12(2):267-278.

[10]Munkholm-Larsen, S., Cao, C.Q., Yan, T.D., 2009. Malignant peritoneal mesothelioma. World J. Gastrointest. Surg., 1(1):38-48.

[11]Pappa, L., Machera, M., Tsanou, E., Damala, C., Peschos, D., Bafa, M., Malamou-Mitsi, V., 2006. Subcutaneous metastasis of peritoneal mesothelioma diagnosed by fine-needle aspiration. Pathol. Oncol. Res., 12(4):247-250.

[12]Sethna, K., Sugarbaker, P.H., 2005. Localized visceral invasion of peritoneal mesothelioma causing intestinal obstruction: a new clinical presentation. Hepatogastroenterology, 52(64):1087-1089.

[13]Sugarbaker, P.H., Welch, L.S., Mohamed, F., Glehen, O., 2003. A review of peritoneal mesothelioma at the Washington Cancer Institute. Surg. Oncol. Clin. N. Am., 12(3):605-621.

[14]Welch, L.S., Acherman, Y.I., Haile, E., Sokas, R.K., Sugarbaker, P.H., 2005. Asbestos and peritoneal mesothelioma among college-educated men. Int. J. Occup. Environ. Health, 11(3):254-258.

[15]Yan, T.D., Popa, R., Brun, E.A., Cerruto, C.A., Sugarbaker, P.H., 2006. Sex difference in diffuse malignant peritoneal mesothelioma. Br. J. Surg., 93(12):1536-1542.

[16]Yang, H., Testa, J.R., Carbone, M., 2008. Mesothelioma epidemiology, carcinogenesis and pathogenesis. Curr. Treat. Options Oncol., 9(2-3):147-157.

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