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CLC number: R735.5

On-line Access: 2011-05-06

Received: 2010-09-16

Revision Accepted: 2010-11-03

Crosschecked: 2011-04-10

Cited: 5

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.5 P.381-384


Malignant peritoneal mesothelioma presenting with persistent high fever

Author(s):  Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang

Affiliation(s):  Department of Family Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China, Department of Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   hsh0906@163.com

Key Words:  Malignant peritoneal mesothelioma, High fever, Metastasis

Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang. Malignant peritoneal mesothelioma presenting with persistent high fever[J]. Journal of Zhejiang University Science B, 2011, 12(5): 381-384.

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author="Li-ying Chen, Ling-xiu Huang, Jin Wang, Yi Qian, Li-zheng Fang",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Malignant peritoneal mesothelioma presenting with persistent high fever
%A Li-ying Chen
%A Ling-xiu Huang
%A Jin Wang
%A Yi Qian
%A Li-zheng Fang
%J Journal of Zhejiang University SCIENCE B
%V 12
%N 5
%P 381-384
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000338

T1 - Malignant peritoneal mesothelioma presenting with persistent high fever
A1 - Li-ying Chen
A1 - Ling-xiu Huang
A1 - Jin Wang
A1 - Yi Qian
A1 - Li-zheng Fang
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 5
SP - 381
EP - 384
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000338

malignant peritoneal mesothelioma (MPM) is a rare tumor that develops in the peritoneum. In this paper, we describe an extremely rare case of MPM metastasizing to the appendix in a 48-year-old female who initially presented with a persistent high fever. The woman reported a slight lower abdominal discomfort which had been relieved by urination for four months. She had lost 5 kg of weight. There was no nausea, vomiting, diarrhea, abdominal pain, or abdominal distension. Many broad spectrum antibiotics were given without relief of fever. Computed tomography (CT) scans revealed a thickened omentum majus and diffused multiple omental nodules. An omentectomy, appendectomy, and adnexectomy were carried out. A gross pathologic specimen of omentum tissue revealed a firm gray-white mass. Microscopic and immunohistochemical examinations confirmed the diagnosis of appendiceal and bilateral adnexal metastases of an MPM. These results suggest that MPM should be considered in the differential diagnosis of unexplained persistent high fever. Awareness of such atypical presentations of mesothelioma may help to make a correct diagnosis.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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