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CLC number: X593

On-line Access: 2011-11-30

Received: 2010-12-19

Revision Accepted: 2011-08-29

Crosschecked: 2011-11-11

Cited: 6

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Journal of Zhejiang University SCIENCE B 2011 Vol.12 No.12 P.969-975


Aircraft noise exposure affects rat behavior, plasma norepinephrine levels, and cell morphology of the temporal lobe

Author(s):  Guo-qing Di, Bing Zhou, Zheng-guang Li, Qi-li Lin

Affiliation(s):  Institute for Environmental Pollution Control Technology, Zhejiang University, Hangzhou 310058, China

Corresponding email(s):   dgq@zju.edu.cn

Key Words:  Aircraft noise, Open field test, Norepinephrine, Neuron, Synapse

Guo-qing Di, Bing Zhou, Zheng-guang Li, Qi-li Lin. Aircraft noise exposure affects rat behavior, plasma norepinephrine levels, and cell morphology of the temporal lobe[J]. Journal of Zhejiang University Science B, 2011, 12(12): 969-975.

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author="Guo-qing Di, Bing Zhou, Zheng-guang Li, Qi-li Lin",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Aircraft noise exposure affects rat behavior, plasma norepinephrine levels, and cell morphology of the temporal lobe
%A Guo-qing Di
%A Bing Zhou
%A Zheng-guang Li
%A Qi-li Lin
%J Journal of Zhejiang University SCIENCE B
%V 12
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%P 969-975
%@ 1673-1581
%D 2011
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1000439

T1 - Aircraft noise exposure affects rat behavior, plasma norepinephrine levels, and cell morphology of the temporal lobe
A1 - Guo-qing Di
A1 - Bing Zhou
A1 - Zheng-guang Li
A1 - Qi-li Lin
J0 - Journal of Zhejiang University Science B
VL - 12
IS - 12
SP - 969
EP - 975
%@ 1673-1581
Y1 - 2011
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1000439

In order to investigate the physiological effects of airport noise exposure on organisms, in this study, we exposed Sprague-Dawley rats in soundproof chambers to previously recorded aircraft-related noise for 65 d. For comparison, we also used unexposed control rats. Noise was arranged according to aircraft flight schedules and was adjusted to its weighted equivalent continuous perceived noise levels (LWECPN) of 75 and 80 dB for the two experimental groups. We examined rat behaviors through an open field test and measured the concentrations of plasma norepinephrine (NE) by high performance liquid chromatography-fluorimetric detection (HPLC-FLD). We also examined the morphologies of neurons and synapses in the temporal lobe by transmission electron microscopy (TEM). Our results showed that rats exposed to airport noise of 80 dB had significantly lower line crossing number (P<0.05) and significantly longer center area duration (P<0.05) than control animals. After 29 d of airport noise exposure, the concentration of plasma NE of exposed rats was significantly higher than that of the control group (P<0.05). We also determined that the neuron and synapsis of the temporal lobe of rats showed signs of damage after aircraft noise of 80 dB exposure for 65 d. In conclusion, exposing rats to long-term aircraft noise affects their behaviors, plasma NE levels, and cell morphology of the temporal lobe.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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