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Received: 2005-03-01

Revision Accepted: 2005-06-09

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Journal of Zhejiang University SCIENCE B 2005 Vol.6 No.10 P.999~1004

10.1631/jzus.2005.B0999


Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)


Author(s):  HE Guo-qing, XIONG Hao-ping, CHEN Qi-he, RUAN Hui, WANG Zhao-yue, TRAORÉ, Lonseny

Affiliation(s):  Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310029, China; more

Corresponding email(s):   gqhe@zju.edu.cn, hpxiong@126.com

Key Words:  Optimization, Supercritical fluid extraction, Flavonoids, Xanthohumol, Hops (Humulus lupulus L.)


HE Guo-qing, XIONG Hao-ping, CHEN Qi-he, RUAN Hui, WANG Zhao-yue, TRAORÉ Lonseny. Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)[J]. Journal of Zhejiang University Science B, 2005, 6(10): 999~1004.

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author="HE Guo-qing, XIONG Hao-ping, CHEN Qi-he, RUAN Hui, WANG Zhao-yue, TRAORÉ Lonseny",
journal="Journal of Zhejiang University Science B",
volume="6",
number="10",
pages="999~1004",
year="2005",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2005.B0999"
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%A HE Guo-qing
%A XIONG Hao-ping
%A CHEN Qi-he
%A RUAN Hui
%A WANG Zhao-yue
%A TRAORÉ
%A Lonseny
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%P 999~1004
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2005.B0999

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T1 - Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.)
A1 - HE Guo-qing
A1 - XIONG Hao-ping
A1 - CHEN Qi-he
A1 - RUAN Hui
A1 - WANG Zhao-yue
A1 - TRAORÉ
A1 - Lonseny
J0 - Journal of Zhejiang University Science B
VL - 6
IS - 10
SP - 999
EP - 1004
%@ 1673-1581
Y1 - 2005
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2005.B0999


Abstract: 
Waste hops are good sources of flavonoids. Extraction of flavonoids from waste hops (SC-CO2 extracted hops) using supercritical fluids technology was investigated. Various temperatures, pressures and concentrations of ethanol (modifier) and the ratio (w/w) of solvent to material were tested in this study. The results of single factor and orthogonal experiments showed that at 50 °C, 25 MPa, the ratio of solvent to material (50%), ethanol concentration (80%) resulted in maximum extraction yield flavonoids (7.8 mg/g). HPLC-MS analysis of the extracts indicated that flavonoids obtained were xanthohumol, the principal prenylflavonoid in hops.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

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