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Journal of Zhejiang University SCIENCE B 2009 Vol.10 No.5 P.391~394

http://doi.org/10.1631/jzus.B0820216


Respiratory face mask: a novel and cost-effective device for use during the application of myocardial ischemia in rats


Author(s):  Yuan YUAN, Fei LI, Yue-min WANG, Rong-qing ZHANG, Li-ping WEI, Hai-chang WANG

Affiliation(s):  Department of Cardiology, Xijing Hospital, the Fourth Military Medical University, Xi’ more

Corresponding email(s):   lifei01@fmmu.edu.cn, wanghc@fmmu.edu.cn

Key Words:  Rats, Respiratory face mask (RFM), Myocardial ischemia, Myocardial infarction


Yuan YUAN, Fei LI, Yue-min WANG, Rong-qing ZHANG, Li-ping WEI, Hai-chang WANG. Respiratory face mask: a novel and cost-effective device for use during the application of myocardial ischemia in rats[J]. Journal of Zhejiang University Science B, 2009, 10(5): 391~394.

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author="Yuan YUAN, Fei LI, Yue-min WANG, Rong-qing ZHANG, Li-ping WEI, Hai-chang WANG",
journal="Journal of Zhejiang University Science B",
volume="10",
number="5",
pages="391~394",
year="2009",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0820216"
}

%0 Journal Article
%T Respiratory face mask: a novel and cost-effective device for use during the application of myocardial ischemia in rats
%A Yuan YUAN
%A Fei LI
%A Yue-min WANG
%A Rong-qing ZHANG
%A Li-ping WEI
%A Hai-chang WANG
%J Journal of Zhejiang University SCIENCE B
%V 10
%N 5
%P 391~394
%@ 1673-1581
%D 2009
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820216

TY - JOUR
T1 - Respiratory face mask: a novel and cost-effective device for use during the application of myocardial ischemia in rats
A1 - Yuan YUAN
A1 - Fei LI
A1 - Yue-min WANG
A1 - Rong-qing ZHANG
A1 - Li-ping WEI
A1 - Hai-chang WANG
J0 - Journal of Zhejiang University Science B
VL - 10
IS - 5
SP - 391
EP - 394
%@ 1673-1581
Y1 - 2009
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0820216


Abstract: 
To shorten operation time and improve survival rate of rats with myocardial ischemia or myocardial infarction, we use a novel device comprised of a face mask and a head/neck retainer in this study. We report the basic design of the novel respiratory face mask (RFM) and evaluate its performance in a rat model of myocardial ischemia. The device is cost-effective and easier to handle than other devices, such as tracheal intubation. Compared with conventional tracheal intubation, we found that RFM shortens operation time significantly while keeping blood indices normal; the mean operation time for rats in the mask group was (32±3) min, and that for the intubation group was (45±7) min (P<0.05). Moreover, the size and shape of the RFM can be changed according to the body weight of rats. In conclusion, RFM is an appropriate device for the establishment of myocardial infarction or ischemia-reperfusion in rats.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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