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Received: 2007-07-09

Revision Accepted: 2007-10-08

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.11 P.839-844


Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus)

Author(s):  CHEN Gui-qian, HU Xiu-fang, SUGAHARA Kunio, CHEN Ji-shuang, SONG Xue-mei, ZHENG Hui-chao, JIANG Yong-qing, HUANG Xin, JIANG Jun-fang, ZHOU Wei-dong

Affiliation(s):  Institute of Bioengineering, Zhejiang Sci-Tech University, Hangzhou 310018, China; more

Corresponding email(s):   wdzhou@zjnm.cn

Key Words:  Neuropeptide Y (NPY), Hypothalamus, Message RNA (mRNA), Meat-type chicken, Layer-type chicken

CHEN Gui-qian, HU Xiu-fang, SUGAHARA Kunio, CHEN Ji-shuang, SONG Xue-mei, ZHENG Hui-chao, JIANG Yong-qing, HUANG Xin, JIANG Jun-fang, ZHOU Wei-dong. Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus)[J]. Journal of Zhejiang University Science B, 2007, 8(11): 839-844.

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author="CHEN Gui-qian, HU Xiu-fang, SUGAHARA Kunio, CHEN Ji-shuang, SONG Xue-mei, ZHENG Hui-chao, JIANG Yong-qing, HUANG Xin, JIANG Jun-fang, ZHOU Wei-dong",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%T Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus)
%A CHEN Gui-qian
%A HU Xiu-fang
%A CHEN Ji-shuang
%A SONG Xue-mei
%A ZHENG Hui-chao
%A JIANG Yong-qing
%A JIANG Jun-fang
%A ZHOU Wei-dong
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 11
%P 839-844
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0839

T1 - Type-dependent differential expression of neuropeptide Y in chicken hypothalamus (Gallus domesticus)
A1 - CHEN Gui-qian
A1 - HU Xiu-fang
A1 - CHEN Ji-shuang
A1 - SONG Xue-mei
A1 - ZHENG Hui-chao
A1 - JIANG Yong-qing
A1 - HUANG Xin
A1 - JIANG Jun-fang
A1 - ZHOU Wei-dong
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 11
SP - 839
EP - 844
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0839

neuropeptide Y (NPY) is one of the most important orexigenic agents in central regulation of feeding behavior, body weight and energy homeostasis in domestic chickens. To examine differences in the hypothalamic NPY between layer-type and meat-type of chickens, which are two divergent kinds of the domestic chickens in feeding behavior and body weight, we detected mRNA levels of NPY in hypothalamic infundibular nucleus (IN), paraventricular nucleus (PVN) and lateral hypothalamic area (LHA) of these two types of chickens using one-step real time RT-PCR. The meat-type chicken had more food daily (about 1.7 folds) and greater body weights (about 1.5 folds) and brain weights than the layer-type chicken at the age of 14 d. In the meat-type of chicken, NPY mRNA levels of the IN and PVN were significantly greater than those of the LHA, and were not significantly different between the IN and PVN. However, in the layer-type of chicken, NPY mRNA levels were significantly greater in the IN than those in the LHA and PVN, and were not significantly different between the PVN and LHA. In all these hypothalamic regions, the layer-type of chicken had significantly higher NPY mRNA levels than the meat-type chicken did. These results suggest the expression of NPY in the hypothalamus has a type-dependent pattern in domestic chickens.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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