CLC number:
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 2023-07-21
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Citations: Bibtex RefMan EndNote GB/T7714
Yanling GUI, Guangfu TANG, Haiqiao MAN, Jiao WANG, Jie HAN, Jiehong ZHAO. Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus[J]. Journal of Zhejiang University Science B, 2023, 24(6): 543-548.
@article{title="Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus",
author="Yanling GUI, Guangfu TANG, Haiqiao MAN, Jiao WANG, Jie HAN, Jiehong ZHAO",
journal="Journal of Zhejiang University Science B",
volume="24",
number="6",
pages="543-548",
year="2023",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2300023"
}
%0 Journal Article
%T Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus
%A Yanling GUI
%A Guangfu TANG
%A Haiqiao MAN
%A Jiao WANG
%A Jie HAN
%A Jiehong ZHAO
%J Journal of Zhejiang University SCIENCE B
%V 24
%N 6
%P 543-548
%@ 1673-1581
%D 2023
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2300023
TY - JOUR
T1 - Transportation of citrinin is regulated by the CtnC gene in the medicinal fungus Monascus purpureus
A1 - Yanling GUI
A1 - Guangfu TANG
A1 - Haiqiao MAN
A1 - Jiao WANG
A1 - Jie HAN
A1 - Jiehong ZHAO
J0 - Journal of Zhejiang University Science B
VL - 24
IS - 6
SP - 543
EP - 548
%@ 1673-1581
Y1 - 2023
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2300023
Abstract: Monascus is one of the most essential microbial resources in China, with thousands of years of history. Modern science has proved that Monascus can produce pigment, ergosterol, monacolin K, γ-aminobutyric acid, and other functionally active substances. Currently, Monascus is used to produce a variety of foods, health products, and pharmaceuticals, and its pigments are widely used as food additives. However, Monascus also makes a harmful polyketide component called citrinin in the fermentation process; citrinin has toxic effects on the kidneys such as teratogenicity, carcinogenicity, and mutagenicity (Gong et al., 2019). The presence of citrinin renders Monascus and its products potentially hazardous, which has led many countries to set limits and standards on citrinin content. For example, the citrinin limit is less than 0.04 mg/kg according to the Chinese document National Standard for Food Safety Food Additive Monascus (GB 1886.181-2016) (National Health and Family Planning Commission of the People’s Republic of China, 2016), and the maximum level in food supplements based on rice fermented with monascus purpureus is 100 µg/kg in the European Union (Commission of the European Union, 2019).
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